MIRA: an R package for DNA methylation-based inference of regulatory activity.
MIRA: an R package for DNA methylation-based inference of regulatory activity.
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DOI:
10.1093/bioinformatics/bty083
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发表时间:
2018-08-01
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影响因子:
--
通讯作者:
Sheffield NC
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文献类型:
--
作者:
Lawson JT;Tomazou EM;Bock C;Sheffield NC
DNA methylation contains information about the regulatory state of the cell. MIRA aggregates genome-scale DNA methylation data into a DNA methylation profile for a given region set with shared biological annotation. Using this profile, MIRA infers and scores the collective regulatory activity for the region set. MIRA facilitates regulatory analysis in situations where classical regulatory assays would be difficult and allows public sources of region sets to be leveraged for novel insight into the regulatory state of DNA methylation datasets. http://bioconductor.org/packages/MIRA.
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影响因子:
12.3
作者:
Yao L;Shen H;Laird PW;Farnham PJ;Berman BP
通讯作者:
Berman BP
DOI:
10.1093/bioinformatics/btv612
发表时间:
2016-02-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Sheffield NC;Bock C
通讯作者:
Bock C
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5.8
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通讯作者:
Tomazou EM
影响因子:
8
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