Structures of merrilactones B and C, novel anislactone-type sesquiterpenes from Illicium merrillianum, and chemical conversion of anislactone B to merrilactone A
Structures of merrilactones B and C, novel anislactone-type sesquiterpenes from Illicium merrillianum, and chemical conversion of anislactone B to merrilactone A
复制标题
DOI：
10.1016/s0040-4020(01)00418-5
复制
发表时间：
2001-05-28
期刊：
影响因子：
2.1
通讯作者：
Fukuyama, Y
中科院分区：
文献类型：
--
作者：
Huang, JM;Yang, CS;Fukuyama, Y
从八角茴香的果皮中分离出两种新的茴香内酯型倍半萜，茴香内酯 B (1) 和 C (2)，以及茴香内酯 A (4) 和 B (5)。通过光谱方法和化学转化阐明了它们的结构，并通过其甲基衍生物的X射线晶体分析确定了merrilactone C的结构。 Merrilactone A (3) 是一种独特的茴香内酯型倍半萜，具有神经突生长促进活性，由茴香内酯 B 有效合成。(C) 2001 Elsevier Science Ltd。保留所有权利。
Two new anislactone-type sesquiterpenes, merrilactones B (1) and C (2) were isolated from the pericarps of Illicium merrillianum along with anislactones A (4) and B (5). Their structures were elucidated by spectroscopic methods and chemical transformation and the structure of merrilactone C was established by X-ray crystallographic analysis of its methyl derivative. Merrilactone A (3), a unique anislactone-type sesquiterpene showing neurite outgrowth promoting activity, was effectively synthesized from anislactone B. (C) 2001 Elsevier Science Ltd. All rights reserved.