Biomolecular NMR: Past and future.

Biomolecular NMR: Past and future.
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DOI:
10.1016/j.abb.2017.05.003
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发表时间:
2017-08-15
影响因子:
3.9
通讯作者:
Westler WM
Westler WM
中科院分区:
生物学3区
文献类型:
--
作者:
Markley JL;Westler WM

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这本特刊的编辑们提出了这个主题,大概是因为我们与生物分子核磁共振结合超过90年的视角。以下是我们对该领域演变的个人经验,我们希望这将说明多年来的变化轨迹。至于未来,人们可以自信地预测,它将涉及意想不到的进步。我们的叙述是彩色的,我们的经验,在使用核磁共振设施的生物医学研究在匹兹堡大学(匹兹堡),并在开发类似的设施在普渡大学(1977年至1984年)和威斯康星大学麦迪逊分校(1984年)。我们很高兴开发NMR技术,并将其提供给这些设施的合作者和用户。我们小组与生物磁共振数据库(BMRB)和全球蛋白质数据库(wwPDB)的合作也是有益的。当然,许多团体对生物分子NfMR的早期生长和发展做出了贡献,我们简短的个人描述当然省略了许多重要的里程碑。
The editors of this special volume suggested this topic, presumably because of the perspective lent by our combined >90-year association with biomolecular NMR. What follows is our personal experience with the evolution of the field, which we hope will illustrate the trajectory of change over the years. As for the future, one can confidently predict that it will involve unexpected advances. Our narrative is colored by our experience in using the NMR Facility for Biomedical Studies at Carnegie-Mellon University (Pittsburgh) and in developing similar facilities at Purdue (1977–1984) and the University of Wisconsin-Madison (1984-). We have enjoyed developing NMR technology and making it available to collaborators and users of these facilities. Our group’s association with the Biological Magnetic Resonance data Bank (BMRB) and with the Worldwide Protein Data Bank (wwPDB) has also been rewarding. Of course, many groups contributed to the early growth and development of biomolecular NfMR, and our brief personal account certainly omits many important milestones.
DOI: 10.1016/j.bpj.2015.07.045
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影响因子: 3.4
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