Impact of mammographic screening on breast cancer diagnosis.
Impact of mammographic screening on breast cancer diagnosis.
复制标题
乳房X线照相筛查对乳腺癌诊断的影响。
DOI：
10.1093/jnci/82.2.153
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Eyre,HJ
中科院分区：
文献类型：
--
作者：
McWhorter,WP;Eyre,HJ
图1.按诊断时的十年年龄发现乳腺癌的方法。使用乳房X线摄影筛查（7）;也就是说，通过乳房X线摄影增加对流行但无症状疾病的检测可能导致高估真实发病率。然而，支持这一假设的唯一证据是间接的。尽管筛查性乳腺X线摄影在检测无症状乳腺癌方面的有效性已在涉及特定人群的试验中得到证实（2，3），但仅通过乳腺X线摄影筛查检测到的新诊断乳腺癌在一般人群中的比例尚不清楚。最近在犹他州进行了这样的研究。犹他州癌症登记处是一个全州范围内以人口为基础的登记处，覆盖范围非常全面。从1987年9月1日至12月31日诊断的所有244例乳腺癌病例的医生都收到了信件，询问癌症是否是通过以下方式首次发现的：1）患者报告可疑发现，2）医生在体检中发现可疑发现，3）在没有临床怀疑的情况下筛查乳房X线检查结果，或4）未知。有时需要多次询问才能追踪了解诊断信息流的医生。
Figure 1. Method of breast cancer discovery by decade of age at diagnosis. to the use of mammographic screening (7); that is, the increased detection of prevalent but asymptomatic disease by mammography may be resulting in an overestimation of true incidence. However, the only evidence supporting this hypothesis has been indirect. Although the effectiveness of screening mammography in detecting asymptomatic breast cancer has been demonstrated in trials involving specific populations (2, 3), the fraction of newly diagnosed breast cancers in the general population that has been detected by means of mammographic screening alone is unknown. Such a study was recently undertaken in Utah.The Utah Cancer Registry is a statewide population-based registry with very complete coverage. Letters were sent to the physicians for all 244 breast cancer cases diagnosed from September 1 through December 31, 1987, asking whether the cancer was first discovered by: 1) the patient's reporting suspicious findings, 2) the physician's discovering suspicious findings on physical examination, 3) screening mammographic findings without prior clinical suspicion, or 4) unknown. Multiple inquiries were sometimes necessary to trace the physician who knew the flow of diagnostic information.