Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT.
Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT.
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DOI：
10.1364/boe.4.000619
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发表时间：
2013-04-01
影响因子：
3.4
通讯作者：
Huber R
中科院分区：
文献类型：
--
作者：
Klein T;André R;Wieser W;Pfeiffer T;Huber R
联合孔径光学相干层析成像（Joint-aperture optical coherence tomography, j -OCT）是一种角度分辨的OCT方法，该方法利用多个被动通道同时探测来自一个主动通道的照明。JA-OCT在不增加样品功率的情况下提高了OCT系统的收集效率和有效灵敏度。此外，JA-OCT在单次采集中提供样品的角度散射信息，因此OCT成像速度不会降低。因此，JA-OCT特别适用于超高速体内成像。将JA-OCT与其他角度分辨技术进行了比较，讨论了联合孔径成像、自适应光学、相干和非相干复合之间的关系。我们在1.68 MHz的轴向扫描速率下展示了人类视网膜的角度分辨成像，并展示了JA-OCT的好处：斑点减少，信号增加和抑制镜面反射和寄生反射。此外，在未来，JA-OCT可能允许重建全多普勒矢量和组织识别分析的角度散射依赖。
Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ultra high speed in-vivo imaging. JA-OCT is compared to other angle-resolved techniques, and the relation between joint aperture imaging, adaptive optics, coherent and incoherent compounding is discussed. We present angle-resolved imaging of the human retina at an axial scan rate of 1.68 MHz, and demonstrate the benefits of JA-OCT: Speckle reduction, signal increase and suppression of specular and parasitic reflections. Moreover, in the future JA-OCT may allow for the reconstruction of the full Doppler vector and tissue discrimination by analysis of the angular scattering dependence.