Synthetic Biology Open Language Visual (SBOL Visual) Version 2.0.
Synthetic Biology Open Language Visual (SBOL Visual) Version 2.0.
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DOI：
10.1515/jib-2017-0074
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发表时间：
2018-03-19
影响因子：
1.9
通讯作者：
Wipat A
中科院分区：
文献类型：
--
作者：
Cox RS;Madsen C;McLaughlin J;Nguyen T;Roehner N;Bartley B;Bhatia S;Bissell M;Clancy K;Gorochowski T;Grünberg R;Luna A;Le Novère N;Pocock M;Sauro H;Sexton JT;Stan GB;Tabor JJ;Voigt CA;Zundel Z;Myers C;Beal J;Wipat A
设计生物有机体的人经常发现用图表进行交流很有用，既可以了解他们正在设计的核酸序列的结构，也可以了解序列特征与其他分子物种之间的功能关系。一些典型的实践和约定已经开始出现这样的图。合成生物学开放语言视觉（SBOL Visual）已被开发为组织和系统化这些约定的标准，以产生用于表达遗传设计的结构和功能的连贯语言。本文档详细介绍了SBOL Visual 2.0版本，该版本建立在之前的SBOL Visual 1.0标准之上，通过扩展图表语法以包括功能相互作用和分子种类，使图表和SBOL数据模型之间的关系显式化，支持符号变体系列，澄清了许多要求和最佳实践，并显着扩展了图表字形的集合。
People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.0 of SBOL Visual, which builds on the prior SBOL Visual 1.0 standard by expanding diagram syntax to include functional interactions and molecular species, making the relationship between diagrams and the SBOL data model explicit, supporting families of symbol variants, clarifying a number of requirements and best practices, and significantly expanding the collection of diagram glyphs.