Are Cirripedia hopeful monsters?: Cytogenetic approach and evidence for a Hox gene cluster in the cirripede crustacean Sacculina carcini
Are Cirripedia hopeful monsters?: Cytogenetic approach and evidence for a Hox gene cluster in the cirripede crustacean Sacculina carcini
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DOI：
10.1007/s00427-006-0088-1
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发表时间：
2006-07-01
影响因子：
2.4
通讯作者：
Deutsch, Jean S.
中科院分区：
文献类型：
--
作者：
Geant, Elodie;Mouchel-Vielh, Emmanuele;Deutsch, Jean S.
自从理查德·戈德施泰特在1933年创造了这个短语以来，“希望的怪物”就一直困扰着进化论。这个短语与发育和进化中的遗传机制直接相关。蔓足类是一种特殊的甲壳类动物，因为它们成年后都没有触角。在以前的一项研究中，旨在描述的Hox基因的Cirripedia的剧目，我们未能分离的abdominal-A基因在三个物种的所有三个蔓足目的代表。为了解决这个问题，是否cirripede的祖先可能是一个“有希望的怪物”所产生的重排的Hox复合体，我们进行了细胞遗传学分析的Hox复合体的cirripede囊癌。我们在这里提出的分子和细胞遗传学证据的分组的Hox基因在一个单一的染色体上。这是第一个直接证据报告的Hox基因在同一染色体上的非昆虫节肢动物物种的分组。
The "hopeful monster" has haunted evolutionary thinking since Richard Goldschmidt coined the phrase in 1933. The phrase is directly related to genetic mechanisms in development and evolution. Cirripedes are peculiar crustaceans in that they all lack abdomens as adults. In a previous study aimed at describing the repertoire of Hox genes of the Cirripedia, we failed to isolate the abdominal-A gene in three species representative of all three cirripede orders. To address the question of whether the cirripede ancestor could have been a "hopeful monster" arising from a rearrangement of the Hox complex, we have performed a cytogenetic analysis of the Hox complex of the cirripede Sacculina carcini. We present here molecular and cytogenetic evidence for the grouping of the Hox genes on a single chromosome. This is the first direct evidence reported for the grouping of Hox genes on the same chromosome in a non-insect arthropod species.