Reduction of rapid eye movement sleep by diurnal and nocturnal seizures in temporal lobe epilepsy
Reduction of rapid eye movement sleep by diurnal and nocturnal seizures in temporal lobe epilepsy
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DOI：
10.1001/archneur.57.3.363
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发表时间：
2000-03-01
影响因子：
--
通讯作者：
Walczak, TS
中科院分区：
文献类型：
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作者：
Bazil, CW;Castro, LHM;Walczak, TS
背景：有短暂、复杂的部分性癫痫发作的患者经常感到疲倦和生产力下降，这些症状在癫痫发作后仍会持续很长时间。一个可能的解释是癫痫发作，即使发生在白天，也会扰乱第二天晚上的睡眠。目的：确定颞叶复杂部分性发作对睡眠结构和白天嗜睡的影响。方法：对颞叶癫痫患者进行视频脑电监测。在无癫痫发作、记录前一天癫痫发作、记录过程中癫痫发作3种情况下记录全夜多导睡眠图。比较癫痫发作与对照状态下每个睡眠阶段的时间百分比、睡眠效率以及到达第一和第二快速眼动(REM)阶段的时间。结果：日间癫痫发作使REM从18%+/-1%降至12%+/-2%(P=0.003)。夜间惊厥使REM从16%+/-1%降至6.8%+/-2%(P
Background: Patients with brief, complex partial seizures frequently suffer from tiredness and decreased productivity that continue well beyond the postictal period. A possible explanation is that seizures, even when occurring during the day, disrupt sleep the following night.Objective: To determine the effect of temporal lobe complex partial seizures on sleep structure and daytime drowsiness.Methods: Patients with temporal lobe epilepsy were admitted for video-electroencephalography monitoring. All night polysomnography was recorded under the following 3 conditions: seizure free, seizure during the day before the recording, and seizure during the recording. Percentage of time in each sleep stage, sleep efficiency, and time to first and second rapid eye movement (REM) period were compared for seizure vs control conditions. Daytime drowsiness was also measured, using a modified maintenance of wakefulness test and 2 subjective drowsiness tests.Results: Daytime seizures reduced REM from 18% +/- 1% to 12% +/- 2% (P = .003). Night seizures reduced REM from 16% +/- 1% to 6.8% +/- 2% (P