Rapid O-glycosidation of phenols with glycosyl fluoride by using the combinational activator, Cp2HfCl2-AgClO4
Rapid O-glycosidation of phenols with glycosyl fluoride by using the combinational activator, Cp2HfCl2-AgClO4
复制标题
使用组合活化剂 Cp2HfCl2-AgClO4 使苯酚与糖基氟发生快速 O-糖苷化
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
Keisuke Suzuki
中科院分区：
文献类型：
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作者：
Takashi Matsumoto;M. Katsuki;Keisuke Suzuki
介绍了一种新的有效的苯酚O-糖苷化方法。在4A分子筛存在下，Cp2HfCl2-AgClO4是糖基氟化物和苯酚偶联反应的高效促进剂，该反应在低温下快速进行，高产率地生成O-芳基糖苷。
A new and efficient method for O-glycosidation of phenols is described. Cp2HfCl2–AgClO4 is a highly effective promoter for the coupling reaction between glycosyl fluoride and phenol in the presence of molecular sieves 4A, which proceeds rapidly at low temperature to give O-aryl glycoside in high yields.