Effect of aerobic exercise on blood pressure: A meta-analysis of randomized, controlled trials
Effect of aerobic exercise on blood pressure: A meta-analysis of randomized, controlled trials
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DOI：
10.7326/0003-4819-136-7-200204020-00006
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发表时间：
2002-04-02
影响因子：
39.2
通讯作者：
He, J
中科院分区：
文献类型：
--
作者：
Whelton, SP;Chin, A;He, J
目的：在观察性流行病学研究和个体临床试验中，体力活动与血压降低有关。这项随机对照试验的荟萃分析旨在确定有氧运动对血压的影响。数据来源：2001 年 9 月之前发表的英文文章。研究选择：54 项随机对照试验（2419 名受试者），其干预组和对照组仅在有氧运动方面存在差异。数据提取：使用标准化方案和数据提取形式，三名研究人员独立提取有关研究设计、样本量、参与者特征、干预类型、随访持续时间的数据，数据合成：在随机效应模型中，将每项试验的数据汇总并按总方差的倒数进行加权。有氧运动与平均收缩压和舒张压显着降低相关（分别为-3.84 mm Hg [95% Cl，-4.97至-2.72 mm Hg]和-2.58 mm Hg [Cl，-3.35至-1.81 mm Hg]）。高血压参与者和血压正常参与者以及超重参与者和正常体重参与者的血压降低与有氧运动相关。结论：有氧运动可以降低高血压和正常血压者的血压。增加有氧运动应被视为改变生活方式以预防和治疗高血压的重要组成部分。
Purpose: Physical activity has been associated with reduced blood pressure in observational epidemiologic studies and individual clinical trials. This meta-analysis of randomized, controlled trials was conducted to determine the effect of aerobic exercise on blood pressure.Data Sources: English-language articles published before September 2001.Study Selection: 54 randomized, controlled trials (2419 participants) whose intervention and control groups differed only in aerobic exercise.Data Extraction: Using a standardized protocol and data extraction form, three of the investigators independently abstracted data on study design, sample size, participant characteristics, type of intervention, follow-up duration, and treatment outcomes.Data Synthesis: In a random-effects model, data from each trial were pooled and weighted by the inverse of the total variance. Aerobic exercise was associated with a significant reduction in mean systolic and diastolic blood pressure (-3.84 mm Hg [95% Cl, -4.97 to -2.72 mm Hg] and -2.58 mm Hg [Cl, -3.35 to -1.81 mm Hg], respectively). A reduction in blood pressure was associated with aerobic exercise in hypertensive participants and normotensive participants and in overweight participants and normal-weight participants.Conclusions: Aerobic exercise reduces blood pressure in both hypertensive and normotensive persons. An increase in aerobic physical activity should be considered an important component of lifestyle modification for prevention and treatment of high blood pressure.