Multidimensional en-Face OCT imaging of the retina
Multidimensional en-Face OCT imaging of the retina
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DOI：
10.1364/oe.17.004112
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发表时间：
2009-03-02
期刊：
影响因子：
3.8
通讯作者：
Podoleanu, Adrian Gh.
中科院分区：
文献类型：
--
作者：
Rosen, Richard B.;Hathaway, Mark;Podoleanu, Adrian Gh.
使用快速T扫描（横向扫描，正面）来建立视网膜的B扫描或C扫描光学相干断层扫描（OCT）图像。几个独特的签名模式的en-face（冠状面）审查结合相关的共焦图像的眼底和B扫描OCT图像。与光谱OCT系统相比，讨论了将T扫描OCT与共焦成像相结合以生成与扫描激光检眼镜（SLO）所生成的图像相似的OCT和共焦图像对的益处。OCT/SLO系统的多通道潜力被证明与另外的第三个硬件通道，获取和生成吲哚菁绿色（ICG）荧光图像。OCT、共焦SLO和ICG荧光图像以两个或三个屏幕格式同时呈现。还包括第四个通道，其显示叠加在相应冠状OCT切片上的ICG序列帧的实时混合，以进行即时多维比较。OSA ISP软件被用来说明同时提供的观点之间的协同作用。这种协同作用通过增强诊断比较来促进信息的解释，并使用SLO通道提供的信息来促进C扫描和B扫描OCT图像内的运动伪影的内部校正。(C)2009年美国光学学会
Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images of the fundus and B-scan OCT images. Benefits in combining T-scan OCT with confocal imaging to generate pairs of OCT and confocal images similar to those generated by scanning laser ophthalmoscopy (SLO) are discussed in comparison with the spectral OCT systems. The multichannel potential of the OCT/SLO system is demonstrated with the addition of a third hardware channel which acquires and generates indocyanine green (ICG) fluorescence images. The OCT, confocal SLO and ICG fluorescence images are simultaneously presented in a two or a three screen format. A fourth channel which displays a live mix of frames of the ICG sequence superimposed on the corresponding coronal OCT slices for immediate multidimensional comparison, is also included. OSA ISP software is employed to illustrate the synergy between the simultaneously provided perspectives. This synergy promotes interpretation of information by enhancing diagnostic comparisons and facilitates internal correction of movement artifacts within C-scan and B-scan OCT images using information provided by the SLO channel. (C) 2009 Optical Society of America