The link between smoking and impotence: Two decades of evidence

The link between smoking and impotence: Two decades of evidence
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DOI:
10.1006/pmed.2001.0830
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发表时间:
2001-06-01
影响因子:
5.1
通讯作者:
Osgood, ND
Osgood, ND
中科院分区:
医学2区
文献类型:
--
作者:
Tengs, TO;Osgood, ND

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背景。现在,反烟草广告以阳痿风险为避免或停止吸烟的理由。然而,科学证据却好坏参半。为了阐明这一争议,我们整理了 2 年来已发表的有关吸烟与阳痿之间联系的数据。方法。我们在 MEDLINE 中检索了从 1980 年至今的研究,报告了阳痿男性受试者中吸烟率的研究。对于每项研究,我们记录了受试者的年龄、居住状态、当前吸烟者的百分比以及收集研究数据的时间段。为了进行比较,我们使用行为危险因素监测系统估计了一般男性人群中特定年龄、州和年份的吸烟率。我们使用随机效应模型进行了荟萃分析。结果。在检查的 1008 篇期刊文章中,我们发现了 19 项研究报告了 3819 名阳痿男性的吸烟习惯。在这 19 项研究中,有 16 项表明吸烟率超过了一般人群。六项规模最大的研究均显示,阳痿男性的吸烟率较高。荟萃分析显示,40% 的阳痿男性目前吸烟,而普通人群中这一比例为 28%。结论。根据近 20 年的证据,吸烟是阳痿的一个重要危险因素。以阳痿作为避免或停止吸烟的理由的反烟草广告是有充分科学事实依据的。 (C) 2001 年美国健康基金会和学术出版社。
Background. Anti-tobacco advertisements now feature the risk of impotence as a reason to avoid or cease tobacco use. The scientific evidence, however, is mixed. To shed light on the controversy, we compiled 2 decades of published data on the link between smoking and impotence.Methods. We searched MEDLINE from 1980 to the present for studies that reported smoking prevalence among impotent male subjects. For each study we recorded the age of subjects, their state of residence, the percentage that were current smokers, and the time period over which study data were collected. For comparison purposes, we estimated age-, state-, and year-specific smoking rates in the general male population using the Behavioral Risk Factors Surveillance System. We performed a meta-analysis using a random effects model.Results. Among the 1008 journal articles examined, we identified 19 studies that reported the smoking habits of 3819 impotent men. Of these 19 studies, 16 indicated a smoking prevalence exceeding that of the general population. The 6 largest studies all revealed a higher prevalence of smoking among impotent men. Mete-analysis reveals that 40% of impotent men were current smokers compared with 28% of men in the general population.Conclusions. Based on almost 2 decades of evidence, tobacco use is an important risk factor for impotence. Anti-tobacco advertisements featuring impotence as a reason to avoid or cease tobacco use are well grounded in scientific fact. (C) 2001 American Health Foundation and Academic Press.