New phenanthrenes from Trigonostemon lii YT Chang
New phenanthrenes from Trigonostemon lii YT Chang
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来自 Trigonostemon lii YT Chang 的新菲
DOI：
10.1016/j.tetlet.2009.03.186
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发表时间：
2009-06-17
影响因子：
1.8
通讯作者：
Hao, Xiao-Jiang
中科院分区：
文献类型：
--
作者：
Hu, Xu-Jia;Wang, Yue-Hu;Hao, Xiao-Jiang
从胡芦巴（Trigonostemonlii）中分离得到三个新的菲类化合物：thrigonosomone A（1），6，9-O-去二甲基胡芦巴酮（2）和thrigonosomone B（3）。通过波谱方法鉴定了它们的结构。通过化学计算和ROESY实验确定了该化合物的相对构型。还评价了化合物1-3的细胞毒性。(C)2009爱思唯尔有限公司保留所有权利。
Three new phenanthrenes, thrigonosomone A (1), 6,9-O-dedimethyltrigonostemone (2), and thrigonosomone B (3) were isolated from Trigonostemon lii. Their structures were elucidated by spectroscopic methods. Thrigonosomone A (1) possessed a novel seven-membered cyclic anhydride moiety, and its relative configuration was determined by chemical computation and ROESY experiment. The cytotoxicity of compounds 1-3 was also evaluated. (C) 2009 Elsevier Ltd. All rights reserved.