Highly selective determination of phenolphthalein by flow injection chemiluminescence method based on a molecular imprinting polymer.
Highly selective determination of phenolphthalein by flow injection chemiluminescence method based on a molecular imprinting polymer.
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DOI：
10.1002/bio.1135
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发表时间：
2009-11
期刊：
影响因子：
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通讯作者：
Jinghua Yu;Lei Ge;P. Dai;Congcong Zhang;Shenguang Ge;Jiadong Huang
中科院分区：
文献类型：
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作者：
Jinghua Yu;Lei Ge;P. Dai;Congcong Zhang;Shenguang Ge;Jiadong Huang
以甲基丙烯酸为功能单体，乙二醇二甲基丙烯酸酯为交联剂，制备了酚酞分子印迹聚合物。利用酚酞对高锰酸钾-盐酸-无水乙醇化学发光体系的猝灭作用，建立了高选择性流动注射化学发光法测定酚酞的新模型。传统的流通池被一种新型的流动路径所取代，该流动路径使用Y形聚甲基丙烯酸甲酯柱，通过该柱同时注入三种反应物。线性范围为1.0 × 10（-8）~ 1.0 × 10（-6）g/mL（r = 0.9978）。检测限为8.9 x 10（-9）g/mL。测定1.0 × 10（-8）g/mL酚酞溶液的相对标准偏差小于2.9%（n = 11）。方法用于真实的样品中酚酞的测定，结果满意。
The phenolphthalein-imprinted polymer was prepared with methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross-linker. Taking advantage of the quenching effect of phenolphthalein on the potassium permanganate-HCl-anhydrous alcohol chemiluminescence system, a new model was established to determine phenolphthalein by a highly selective flow injection chemiluminescence method. The traditional flow-though cell was replaced with a novel flow path using a Y-shaped polymethyl methacrylate column, through which the three reactants were injected simultaneously. The linear range of this assay was from 1.0 x 10(-8) to 1.0 x 10(-6) g/mL (r = 0.9978). The limit of detection was 8.9 x 10(-9) g/mL. The relative standard deviation for the determination of 1.0 x 10(-8) g/mL phenolphthalein solution was below 2.9% (n = 11). The proposed method was applied to the determination of phenolphthalein in real samples with satisfactory results.