ANASTOMOTIC INTEGRITY AFTER OPERATIONS FOR LARGE-BOWEL CANCER - A MULTICENTER STUDY
ANASTOMOTIC INTEGRITY AFTER OPERATIONS FOR LARGE-BOWEL CANCER - A MULTICENTER STUDY
复制标题
DOI：
10.1136/bmj.281.6237.411
复制
发表时间：
1980-01-01
影响因子：
--
通讯作者：
KEARNEY, G
中科院分区：
文献类型：
--
作者：
FIELDING, LP;STEWARTBROWN, S;KEARNEY, G
对 1466 名接受过大肠腺癌切除术的患者进行了临床明显的吻合口裂开研究。吻合口漏的总体发生率为 13%，但不同外科医生的发生率有所不同（范围为 0.5% 至超过 30%）。吻合口未能初次愈合的患者的发病率和死亡率显着较高。如果将这些结果外推到国家水平，应该可以通过获得更接近无渗漏患者的结果来将大肠癌切除术后的总体术后死亡率降低 2%，并实现发病率的显着降低。这两个因素在临床上都很重要，综合起来可以节省可观的收入。
Clinically evident anastomotic dehiscence was studied in 1466 patients who had undergone resection of a large-bowel adenocarcinoma. The overall incidence of anastomotic leakage was 13%, but the incidence varied between surgeons (range 0.5% to over 30%). Morbidity and mortality were significantly higher in those patients in whom the anastomosis failed to heal primarily. If these results are extrapolated to the national level, it should be possible by achieving results closer to those in patients without leakage to reduce overall post-operative mortality after resection of large-bowel cancer by 2% and to achieve an appreciable reduction in morbidity. Both factors are clinically important and, taken together, could result in appreciable saving of revenue.