Cortical processing of tactile language in a postlingually deaf-blind subject
Cortical processing of tactile language in a postlingually deaf-blind subject
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DOI：
10.1097/00001756-200402090-00015
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发表时间：
2004-02-09
期刊：
影响因子：
1.7
通讯作者：
Kubo, T
中科院分区：
文献类型：
--
作者：
Osaki, Y;Doi, K;Kubo, T
我们比较了由脑磁图(MEG)检测到的语言后失聪受试者和6名正常志愿者在单词和非单词的触觉呈现时的神经激活。当触觉词呈现到聋盲者的右手时，左侧中央后回、双侧额下回、左侧后颞叶、右侧前颞叶、双侧枕中回被激活。在正常志愿者中没有观察到这组激活区域，尽管检测到了这些区域的几种组合的激活。正电子发射断层扫描证实了聋盲受试者脑磁图激活区的位置。我们的结果表明，聋盲受试者通过增强认知和语义加工的皮层激活，参与了对触觉语言的理解。
We compared neural activation detected by magnetoencephalography (MEG) during tactile presentation of words and non-words in a postlingually deaf-blind subject and six normal volunteers. The left postcentral gyrus, bilateral inferior frontal gyri, left posterior temporal lobe, right anterior temporal lobe, bilateral middle occipital gyri were activated when tactile words were presented to the right hand of the deaf-blind subject. This set of activated regions was not observed in the normal volunteers, although activation of several combinations of these regions was detected. Positron emission tomography confirmed the location of the MEG-activated areas in the deaf-blind subject. Our results demonstrated that the deaf-blind subject is heavily involved in interpreting tactile language by enhancing cortical activation of cognitive and semantic processing.