EIGENSCHAFTEN DES VIRUS DER EQUINEN ARTERITIS
EIGENSCHAFTEN DES VIRUS DER EQUINEN ARTERITIS
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DOI：
10.1159/000161861
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发表时间：
1965-01-01
期刊：
影响因子：
--
通讯作者：
BURKI, F
中科院分区：
文献类型：
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作者：
BURKI, F
马动脉炎病毒（Doll）被证明是一种直径远小于100 μ m的RNA-脂病毒。作者在瑞士（Bibuna）从患有Pferdestaupe的马的结膜/鼻拭子中分离的菌株显示出相同的特性，并且在血清学上与美国比塞罗斯菌株密切相关或相同。因此，EAV将首次在美国以外被分离出来。瑞士Bibuna株在马肾细胞中显示出明显的前带抑制，这可能是由于干扰素、不完全病毒或毒性因子所致。迄今为止，尚未证明与HCV或BVD病毒（与EAV显示出一定相似性的因子）的体外交叉反应。已确定的事实不允许将EAV、HCV或BVD明确地归入虫媒病毒或粘病毒组。除非进一步的数据将这3种病原体明确归入其中一组，否则建议将其与人肝炎病毒一起归入血病毒组（姆克林）。
Equine Arteritis Virus (Doll) was shown to be an RNA-Lipovirus of considerably less than 100 m[mu] diameter. A strain isolated in Switzerland (Bibuna) by the author from a conjunctival/ nasal swab of a horse suffering from Pferdestaupe shows the same properties and is serologically closely related to or identical with the American Bucyrus strain. Hence EAV would have been isolated for the first time outside the USA. The Swiss Bibuna strain shows in horse kidney cells marked prozonal inhibition either due to interferon, to incomplete virus or to a toxic factor. In vitro cross reactions with HCV or BVD viruses, agents showing certain similarities with EAV, could not be demonstrated till now. Established facts do not permit to range EAV, nor HCV or BVD, unequivocally within the groups of Arboviruses or Myxoviruses. Unless further data firmly place these 3 agents into one of these groups, it is suggested that they be put into the Haemovirus group (McLean), together with human hepatitis viruses.