PREDICTING THE DISABILITY OF FIRST-TIME STROKE SUFFERERS AT 1 YEAR - 12-MONTH FOLLOW-UP OF A POPULATION-EASED COHORT IN SOUTHEAST ENGLAND

PREDICTING THE DISABILITY OF FIRST-TIME STROKE SUFFERERS AT 1 YEAR - 12-MONTH FOLLOW-UP OF A POPULATION-EASED COHORT IN SOUTHEAST ENGLAND
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DOI:
10.1161/01.str.25.2.352
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发表时间:
1994-02-01
期刊:
影响因子:
8.3
通讯作者:
BURNEY, PGJ
BURNEY, PGJ
中科院分区:
医学1区
文献类型:
--
作者:
TAUB, NA;WOLFE, CDA;BURNEY, PGJ

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背景和目的本研究的目的是预测年龄小于75岁的首次脑卒中患者1年时的功能结局与脑卒中严重程度和人口统计学特征的关系。方法1989年8月在英格兰东南部的三个地区建立了人口登记册,并由卒中登记处的现场工作人员、全科医生和康复医生通知。使用Barthel指数评估最大损害时以及卒中后3个月和12个月的日常生活活动。结果639例脑卒中患者中,392例无致残史,3个月时经残疾评定,其中重度残疾34例(9%),中度残疾60例(15%)。初始尿失禁是残疾的最佳单一预测因子,敏感性为60%,特异性为78%。225例患者(35%)有资格接受12个月的随访; 11%有中度或重度残疾,初始尿失禁是最好的预测因素。结论:本研究没有证据表明人口统计学特征与中风幸存者的残疾状况在中期内存在关联。多变量残疾预测指标与卒中后24小时内尿失禁相比没有优势。在评估中风患者的中期需求时,这项基于大规模人群的研究对残疾患病率的估计是相关的。
Background and Purpose The purpose of this study was to predict the functional outcome at 1 year of first-time stroke patients aged younger than 75 years in relation to the severity of stroke and demographic characteristics. Methods Population registers in three districts of southeast England were established in August 1989, with notification by stroke registry field-workers, general practitioners, and rehabilitation practitioners. Assessments were made using the Barthel index for activities of daily living at the time of maximum impairment and at 3 and 12 months after the stroke. Results Of 639 registered stroke patients, 392 without previous disability survived and were assessed for disability at 3 months, of whom 34 (9%) were Severely disabled and 60 (15%) moderately disabled. Initial incontinence was the best single predictor of disability with a sensitivity of 60% and a specificity of 78%. Two hundred twenty-five patients (35%) were eligible for 12-month follow-up; 11% had moderate or severe disability, for which initial incontinence was the best predictor. Conclusions There is no evidence from this study of an association between demographic characteristics and the disability status of stroke survivors in the medium term. Multivariable predictors of disability had little advantage over incontinence within 24 hours of the stroke. The estimates of the prevalence of disability from this large population-based study are relevant when assessing the medium-term needs of stroke patients.