Sonomyography Analysis on Thickness of Skeletal Muscle During Dynamic Contraction Induced by Neuromuscular Electrical Stimulation: A Pilot Study
Sonomyography Analysis on Thickness of Skeletal Muscle During Dynamic Contraction Induced by Neuromuscular Electrical Stimulation: A Pilot Study
复制标题
神经肌肉电刺激引起的动态收缩期间骨骼肌厚度的声肌图分析：初步研究
DOI：
10.1109/tnsre.2016.2556687
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发表时间：
2017
影响因子：
4.9
通讯作者：
Ming Dong
中科院分区：
文献类型：
--
作者：
Qiu Shuang;Feng Jing;Xu Jiapeng;Xu Rui;Zhao Xin;Zhou Peng;Qi Hongzhi;Zhang Lixin;Ming Dong
目的：神经肌肉电刺激(NMES)刺激骨骼肌引起收缩，已被广泛应用于瘫痪肌肉的功能恢复。然而，NMES诱导的刺激肌肉的结构变化仍不是很清楚。本研究应用声学图(SMG)来评估NMES诱导和自主运动下的肌肉结构。对7名健康受试者的股四头肌进行8个周期的伸膝运动测试，记录伸膝过程中的SMG和膝关节角度。建立了最小二乘支持向量机(LS-SVM)最小二乘支持向量机(LS-SVM)模型，并利用NMES采集的6个周期的数据集对其进行训练，其余数据用于检验。从超声图像中提取肌肉厚度的变化，并比较NMES诱发的收缩和自主收缩之间的差异，并使用最小二乘支持向量机建立动态膝关节角度与SMG信号之间的关系模型。在NMES诱发的收缩中，肌肉厚度与关节角度显著相关，股中间肌(VI)厚度与股直肌(RF)厚度显著负相关。此外，自愿和NMES诱发的宫缩之间也有显著差异。基于RF厚度和膝关节角度的最小二乘支持向量机模型比基于VI厚度和膝关节角度或总厚度和膝关节角度的模型具有更好的性能。这表明射频厚度与膝关节角度之间存在着很强的关系。这些结果为射频厚度在优化NMES系统以及测量NMES下的肌肉状态方面的潜在应用提供了直接证据。
Goal: Neuromuscular electrical stimulation (NMES) that stimulates skeletal muscles to induce contractions has been widely applied to restore functions of paralyzed muscles. However, the architectural changes of stimulated muscles induced by NMES are still not well understood. The present study applies sonomyography (SMG) to evaluate muscle architecture under NMES-induced and voluntary movements. The quadriceps muscles of seven healthy subjects were tested for eight cycles during an extension exercise of the knee joint with/without NMES, and SMG and the knee joint angle were recorded during the process of knee extension. A least squares support vector machine (LS-SVM) LS-SVM model was developed and trained using the data sets of six cycles collected under NMES, while the remaining data was used to test. Muscle thickness changes were extracted from ultrasound images and compared between NMES-induced and voluntary contractions, and LS-SVM was used to model a relationship between dynamical knee joint angles and SMG signals. Muscle thickness showed to be significantly correlated with joint angle $(P< 0.05)$ in NMES-induced contractions, and a significant negative correlation was observed between Vastus intermedius (VI) thickness and rectus femoris (RF) thickness. In addition, there was a significant difference between voluntary and NMES-induced contractions $(P< 0.05)$ . The LS-SVM model based on RF thickness and knee joint angle provided superior performance compared with the model based on VI thickness and knee joint angle or total thickness and knee joint angle. This suggests that a strong relation exists between the RF thickness and knee joint angle. These results provided direct evidence for the potential application of RF thickness in optimizing NMES system as well as measuring muscle state under NMES.