Cervix Cancer in Sub-Saharan Africa: An Assessment of Cervical Cancer Management.
Cervix Cancer in Sub-Saharan Africa: An Assessment of Cervical Cancer Management.
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DOI：
10.1200/go.20.00079
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发表时间：
2021-03
影响因子：
4.5
通讯作者：
Gaffney DK
中科院分区：
文献类型：
--
作者：
Burt LM;McCormak M;Lecuru F;Kanyike DM;Bvochora-Nsingo M;Ndlovu N;Scott AA;Anorlu RI;Sharma V;Plante M;Nyongesa C;Tigeneh W;Fakie N;Suneja G;Gaffney DK
欠发达国家承担着大多数宫颈癌的负担，但获得适当的治疗可能具有挑战性。本报告评估了撒哈拉以南非洲地区宫颈癌的当前管理，以更好地了解欠发达国家在管理宫颈癌方面的需求。一个前和后的调查被发送到所有中心参加宫颈癌研究网络的第四届年度研讨会。调查前和调查后评估了人乳头瘤病毒和艾滋病毒筛查、可用于检查和/或治疗的资源、治疗后勤、结果和临床试验的招募。对调查答复进行了描述性分析。来自12个撒哈拉以南国家的29个中心每年约有300例宫颈癌新发病例。在接受调查的国家中，55%的国家有人乳头瘤病毒疫苗接种计划，每个地区估计有30%（范围，0%-65%）的妇女参加了宫颈癌筛查计划。在患者的检查中，43%的中心能够获得正电子发射断层扫描和计算机断层扫描，79%的中心具有磁共振成像能力。在进行手术时，这些中心中有88%的外科医生具有进行肿瘤手术的专业知识。96%的中心接受了放射治疗，86%的中心接受了化疗。临床试验在4%的中心开放。在撒哈拉以南非洲地区，宫颈癌患者的筛查、检查和管理方面取得了重大进展;但仍需改进。临床试验的招募仍然是一场斗争。参与者希望在宫颈癌研究网络的持续支持下招募患者进行临床试验。
Underdeveloped nations carry the burden of most cervical cancer, yet access to adequate treatment can be challenging. This report assesses the current management of cervical cancer in sub-Saharan Africa to better understand the needs of underdeveloped nations in managing cervical cancer. A pre- and postsurvey was sent to all centers participating in the Cervical Cancer Research Network's 4th annual symposium. The pre- and postsurvey evaluated human papillomavirus and HIV screening, resources available for workup and/or treatment, treatment logistics, outcomes, and enrollment on clinical trials. Descriptive analyses were performed on survey responses. Twenty-nine centers from 12 sub-Saharan countries saw approximately 300 new cases of cervical cancer yearly. Of the countries surveyed, 55% of countries had a human papillomavirus vaccination program and 30% (range, 0%-65%) of women in each region were estimated to have participated in a cervical cancer screening program. In the workup of patients, 43% of centers had the ability to obtain a positron emission tomography and computed tomography scan and 79% had magnetic resonance imaging capabilities. When performing surgery, 88% of those centers had a surgeon with an expertise in performing oncological surgeries. Radiation therapy was available at 96% of the centers surveyed, and chemotherapy was available in 86% of centers. Clinical trials were open at 4% of centers. There have been significant advancements being made in screening, workup, and management of patients with cervical cancer in sub-Saharan Africa; yet, improvement is still needed. Enrollment in clinical trials remains a struggle. Participants would like to enroll patients on clinical trials with Cervical Cancer Research Network's continuous support.