Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism
Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism
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DOI：
10.1126/science.273.5277.948
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发表时间：
1996-08-16
期刊：
影响因子：
56.9
通讯作者：
Feldmann, KA
中科院分区：
文献类型：
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作者：
Bennett, MJ;Marchant, A;Feldmann, KA
植物激素生长素调节各种发育过程，包括根的形成、维管发育和向地性。AUX 1基因内的突变赋予生长素抗性的根生长表型和废除根向重力弯曲。多肽序列与氨基酸渗透酶的相似性表明，AUX 1介导氨基酸样信号分子的转运。吲哚-3-乙酸是高等植物中生长素的主要形式，其结构类似于色氨酸，并且可能是AUX 1基因产物的底物。所克隆的AUX 1基因能够恢复转基因植物的生长素反应性。在空间上，AUX 1表达于根尖组织，调节根向重力弯曲。
The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid-like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.