Risk factors for type II diabetes and diabetic retinopathy in a Mexican-American population: Proyecto VER
Risk factors for type II diabetes and diabetic retinopathy in a Mexican-American population: Proyecto VER
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DOI：
10.1016/s0002-9394(02)01595-7
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发表时间：
2002-09-01
影响因子：
4.2
通讯作者：
Snyder, R
中科院分区：
文献类型：
--
作者：
West, SK;Munoz, B;Snyder, R
目得：II型糖尿病和糖尿病视网膜病变的危险因素是在一项以墨西哥人、美国人为基础的研究中确定的。设计：项目VER（视觉，评价和研究）是一个横向，横断面研究在图森和诺加莱斯，亚利桑那州，年龄40岁及以上的自我描述的西班牙裔人口的随机样本。在6，659例合格受试者中，4，774例（72%）参与了家庭问卷和诊所访视。糖尿病定义为自身、医生诊断报告或血红蛋白A（1c）值大于或等于7.0%。仅纳入II型糖尿病。糖尿病视网膜病变评估立体眼底照片的所有人与糖尿病。问题被问及人口统计学，个人，社会经济学，糖尿病相关的variables.RESULTS：1023（21.4%）的样本有II型糖尿病，68%的低收入组（年收入低于20,000美元）。糖尿病与美国原住民血统、较高的文化适应、低收入、受教育程度低以及经年龄和性别调整后的体重指数增加有关。与已知的糖尿病患者相比，以前未发现的糖尿病患者更有可能没有定期的护理来源，没有保险，目前吸烟。只有低收入与增殖性视网膜病变相关，一旦调整其他因素（比值比[OR] = 3.93，95%，置信限[CL] = 1.31-11.80）。结论：一些社会经济和其他因素与糖尿病相关，但很少与糖尿病视网膜病变相关。与收入较高的人群相比，低收入人群患糖尿病和糖尿病眼部并发症的风险似乎更大。需要在这一人群中进行进一步的纵向研究来确认相关性。(C)2002年，Elsevier Science Inc. All rights reserved.
PURPOSE: Risk factors for type II diabetes and diabetic retinopathy were determined in a population-based study of Mexican,Americans.DESIGN: Proyecto VER (Vision, Evaluation, and Research) is a cross,sectional study in a random sample of the self-described Hispanic populations in Tucson and Nogales, Arizona, age 40 and older.METHODS: Of 6,659 eligible subjects, 4,774 (72%) participated in the home questionnaire and clinic visit. Diabetes was defined as self,report of a physician diagnosis or hemoglobin A(1c) value of greater than or equal to7.0%. Only type II diabetes was included. Diabetic retinopathy was assessed on stereo fundus photographs of all persons with diabetes. Questions were asked about demographic, personal, socioeconomic, and diabetes related variables.RESULTS: 1023 (21.4%) of the sample had type II diabetes, and 68% were in the low-income group (annual income less than $20,000). Diabetes was associated with Native-American ancestry, higher acculturation, low income, less education, and increasing body mass index after age and gender adjustment. Persons with previously undiscovered diabetes were more likely to have no regular source of care, no insurance, and currently smoke compared with persons with known diabetes. Only low income was related to proliferative retinopathy, once adjusted for other factors (odds ratio [OR] = 3.93, 95%, confidence limitations [CL] = 1.31-11.80).CONCLUSIONS: Several socioeconomic and other factors were associated with diabetes, but few were related to diabetic retinopathy. Persons in the low-income group appeared to be at greater risk of diabetes and the ocular complications of diabetes compared with those with more income. Further longitudinal studies in this population are needed to confirm the associations. (C) 2002 by Elsevier Science Inc. All rights reserved.