Sensitivity and specificity of the Patient Health Questionnaire-9 (PHQ-9) among adults from the general population
Sensitivity and specificity of the Patient Health Questionnaire-9 (PHQ-9) among adults from the general population
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DOI：
10.1590/s0102-311x2013001200006
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发表时间：
2013-08-01
期刊：
影响因子：
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通讯作者：
Matijasevich, Alicia
中科院分区：
文献类型：
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作者：
Santos, Iná S.;Tavares, Beatriz Franck;Matijasevich, Alicia
这项以人群为基础的研究主要关注患者健康问卷-9（PHQ-9）在巴西南里奥格兰德州佩尔蒂尼奥市筛查一般人群中重度抑郁发作的有效性。通过多阶段抽样选择住户，并邀请成年人（>= 20岁）参加。金标准是由精神病学家和心理学家应用的结构化诊断迷你国际神经精神访谈（MINI）。PHQ-9和MINI都在受试者家中使用。在总共447名参与者（191名男性和256名女性）中，连续分析将>= 9确定为具有最高灵敏度（77.5%; 61.5-89.2）和特异性（86.7%; 83.0-89.9）的截止点。使用测试算法将灵敏度降低至42.5%（27.0-59.1），而特异性增加至95.3%（92.8-97.2）。PHQ-9被证明适用于筛查重度抑郁发作。对于更高的敏感性，连续评分的PHQ-9证明比在社区筛查重度抑郁发作的算法更充分。
This population-based study focused on the validity of the Patient Health Questionnaire-9 (PHQ-9) for screening major depressive episodes in the general population in Pelotas, Rio Grande do Sul State, Brazil. Households were selected by multi-stage sampling, and adults (>= 20 years) were invited to participate. The gold standard was the structured diagnostic Mini International Neuropsychiatric Interview (MINI), applied by psychiatrists and psychologists. Both the PHQ-9 and the MINI were applied in the subjects' homes. In a total of 447 participants (191 men and 256 women), the continuous analysis identified >= 9 as the cutoff point with the highest sensitivity (77.5%; 61.5-89.2) and specificity (86.7%; 83.0-89.9). Use of the test's algorithm decreased the sensitivity to 42.5% (27.0-59.1), while the specificity increased to 95.3% (92.8-97.2). The PHQ-9 proved appropriate for screening major depressive episodes. For greater sensitivity, the continuously scored PHQ-9 proved more adequate than the algorithm for screening major depressive episodes in the community.