Longitudinal erythronychia with distal subungual keratosis: onychopapilloma of the nail bed and Bowen's disease
Longitudinal erythronychia with distal subungual keratosis: onychopapilloma of the nail bed and Bowen's disease
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DOI：
10.1046/j.1365-2133.2000.03602.x
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发表时间：
2000-07-01
影响因子：
10.3
通讯作者：
Perrin, C
中科院分区：
文献类型：
--
作者：
Baran, R;Perrin, C
我们对16名受试者进行了纵向红甲状腺活检，发现14例甲状乳头状瘤和2例鲍温氏病。除了红甲症(或有时由碎片出血组成的间断线)外，共同的临床特征是典型的甲床纵向明显的隆起，在远端甲床扩张为甲下角化症，以及相关的局限性甲裂。这种类型的鲍温氏病的表现以前没有报道过。在所有甲床甲乳头状瘤中，棘皮病和乳头状瘤病都很明显，并与与甲基质相同的角化带相关。此外，我们在两个甲乳头状瘤中发现了多核巨细胞。因此，我们建议将“局限性远端多核细胞甲下角化病”改为“甲乳头状瘤”(指甲性乳头状瘤)。
We biopsied longitudinal erythronychia in 16 subjects, and found an onychopapilloma in 14 cases and Bowen's disease in the remaining two. Shared clinical features in addition to erythronychia (or sometimes an interrupted line made up of splinter haemorrhages) were typically a longitudinal marked ridge of the nail bed expanded at the distal nail bed as subungual keratosis, and associated localized onycholysis. The presentation of Bowen's disease in this pattern has not been previously reported. In all cases of onychopapilloma of the nail bed, acanthosis and papillomatosis were evident, and were associated with a keratogenous zone identical to the nail matrix. In addition, we found multinucleate giant cells in two onychopapillomas. We have therefore suggested that the term 'localized, distal, subungual keratosis with multinucleate cells' should be replaced by 'onychopapilloma' (nail-producing papilloma).