In-line phase-contrast imaging of a biological specimen using a compact laser-Compton scattering-based x-ray source
In-line phase-contrast imaging of a biological specimen using a compact laser-Compton scattering-based x-ray source
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DOI：
10.1063/1.2903148
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发表时间：
2008-04
影响因子：
4
通讯作者：
H. Ikeura-Sekiguchi;R. Kuroda;M. Yasumoto;H. Toyokawa;M. Koike;K. Yamada;F. Sakai;K. Mori;K. Maruyama;H. Oka;T. Kimata
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文献类型：
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作者：
H. Ikeura-Sekiguchi;R. Kuroda;M. Yasumoto;H. Toyokawa;M. Koike;K. Yamada;F. Sakai;K. Mori;K. Maruyama;H. Oka;T. Kimata
激光康普顿散射（LCS）X射线源最近吸引了很多关注，因为它们在当地医疗设施的潜在用途，因为它们可以产生超短脉冲，高亮度，准单色硬X射线与小的源尺寸。为促进临床成像，研究了利用所研制的紧凑型LCS-X在AIST中对大鼠腰椎“厚”生物标本进行同轴相衬成像的可行性。在更高质量的图像中，椎骨棘突的解剖细节比传统的吸收射线照相术更清晰可见。结果表明，可以使用LCS-X进行相衬射线照相术。
Laser-Compton scattering (LCS) x-ray sources have recently attracted much attention for their potential use at local medical facilities because they can produce ultrashort pulsed, high-brilliance, and quasimonochromatic hard x rays with a small source size. The feasibility of in-line phase-contrast imaging for a “thick” biological specimens of rat lumbar vertebrae using the developed compact LCS-X in AIST was investigated for the promotion of clinical imaging. In the higher-quality images, anatomical details of the spinous processes of the vertebrae are more clearly observable than with conventional absorption radiography. The results demonstrate that phase-contrast radiography can be performed using LCS-X.