Case Study: Community Engagement and Clinical Trial Success: Outreach to African American Women.
Case Study: Community Engagement and Clinical Trial Success: Outreach to African American Women.
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案例研究：社区参与和临床试验成功：向非裔美国妇女宣传。
DOI：
10.1111/cts.12264
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发表时间：
2015-08
期刊：
影响因子：
--
通讯作者：
Shibao CA
中科院分区：
文献类型：
--
作者：
Johnson DA;Joosten YA;Wilkins CH;Shibao CA
这份简短的报告考察了社区参与原则和方法的使用如何增强临床试验的招募和保留。咨询了社区参与研究核心(CERC)，这是一个由CTSA支持的资源，旨在促进社区参与临床和转化性研究，以提供临床试验实施方面的援助，特别是加强目标人群--非洲裔美国妇女的参与。CERC的主要建议包括1)召开社区参与工作室(CES)，2)重新设计招聘广告，3)简化用于解释研究范围的语言，4)为参与者提供交通工具。作为这些干预措施的结果，制定了招募、登记和留住参与者的综合战略。在研究团队实施计划后，招生人数增加了78%，提前16个月实现了招聘目标。参与者保留率和研究药物依从性为100%。我们的结论是，社区参与对于制定有效的多方面计划至关重要，以改善临床试验中代表性不足群体的招募。
This brief report examines how the use of community engagement principles and approaches enhanced clinical trial recruitment and retention. The Community Engaged Research Core (CERC), a CTSA-supported resource designed to facilitate community involvement in clinical and translational research, was consulted to provide assistance with the implementation of the clinical trial, and specifically to enhance participation of the target population- African American women. CERC's key recommendations included 1) convene a Community Engagement Studio (CES), 2) redesign the recruitment advertisement, 3) simplify the language used to explain the scope of the study, and 4) provide transportation for participants. As a result of these interventions, a comprehensive strategy to recruit, enroll, and retain participants was formulated. After implementation of the plan by the study team, enrollment increased 78% and recruitment goals were met 16 months ahead of schedule. Participant retention and study drug adherence was 100%. We conclude that community engagement is essential to the development of an effective multi-faceted plan to improve recruitment of underrepresented groups in clinical trials.