Changes in cerebellar activation pattern during two successive sequences of saccades
Changes in cerebellar activation pattern during two successive sequences of saccades
复制标题
两次连续眼跳序列期间小脑激活模式的变化
作者：
T. Stephan;A. Mascolo;T. Yousry;S. Bense;T. Brandt;M. Dieterich
在12名熟悉研究范式的健康志愿者中，通过视觉引导的来回扫视，确定了两次连续fMRI扫描运行的小脑激活模式的变化。组和单个受试者分析显示，小脑旁正中蚓部（悬雍垂、扁桃体、结节、叶/降）持续激活，这反映了两次运行中持续的眼部运动活动。在第二次跑步中发现的小脑半球激活的显着减少最好解释为注意力下降或运动优化和学习的影响。在连续两次实验中，小脑激活模式的显著、系统性变化是不被预期的，因为眼运动任务是简单、熟悉和高度自动化的。这些发现表明，类似的影响可能会偏向其他小脑激活研究，其中感觉运动任务在一个单一的会话中重复。Hum.脑图谱16：63-70，2002年。© 2002 Wiley利斯公司
The changes in the cerebellar activation pattern of two successive fMRI scanning runs were determined for visually guided to‐and‐fro saccades in 12 healthy volunteers familiar with the study paradigm. Group and single subject‐analyses revealed a constant activation of the paramedian cerebellar vermis (uvula, tonsils, tuber, folium/declive), which reflects constant ocular motor activity in both runs. A significant decrease in activation of the cerebellar hemispheres found in the second run is best explained by either a decrease in attention or the effects of motor optimization and learning. The significant, systematic changes of the cerebellar activation pattern in two successive runs were not expected, because the ocular motor task was simple, familiar, and highly automated. These findings indicate that similar effects may bias other cerebellar activation studies, in which sensorimotor tasks are repeated in a single session. Hum. Brain Mapping 16:63–70, 2002. © 2002 Wiley‐Liss, Inc.
影响因子：
2.5
作者：
FUCHS, AF;ROBINSON, FR;STRAUBE, A
通讯作者：
STRAUBE, A