Case-Matched Analysis of Totally Laparoscopic Versus Open Liver Resection for HCC: Short and Middle Term Results
Case-Matched Analysis of Totally Laparoscopic Versus Open Liver Resection for HCC: Short and Middle Term Results
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DOI：
10.1002/jso.21541
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发表时间：
2010-07-01
影响因子：
2.5
通讯作者：
Ferla, Gianfranco
中科院分区：
文献类型：
--
作者：
Aldrighetti, Luca;Guzzetti, Eleonora;Ferla, Gianfranco
背景和目的：腹腔镜作为一种安全的肝肿瘤切除方法正在被越来越多的人接受。本研究的目的是评估肝癌患者行小肝切除术的手术效果和中期生存率。于2005年9月至2009年1月接受腹腔镜肝切除术的患者，与同期接受开放切除术（OR）的对照组16例患者进行比较。两组在切除术类型、肿瘤大小和肝硬化严重程度方面相匹配。1例患者改用腹腔镜入路，手术时间缩短（150 mm, P 0.044），毛巾失血量缩短（258 ml, P 0.08），手术发病率和死亡率无差异，腹腔镜入路住院时间缩短（63 d）。平均随访32个月后，腹腔镜组疾病树生存期为40.2个月，总生存期为23.3个月。(1)结论：腹腔镜下肝细胞癌切除术在选定的患者中是可行和安全的，可以获得良好的手术效果，在总生存率和无病生存率方面相似。中华外科杂志，2010,32(2):581 - 586。公司
Background and Objectives: Laparoscopy is gaining acceptance as a safe procedure for resection of liver neoplasms The aim of this study is to evaluate surgical results and mid-term survival of minor hepatic resection performed for HCCMethods: Data of 16 patients with HCC. undergoing laparoscopic hepatectomy from September 2005 to January 2009, were compared to a control group of 16 patients who underwent open resection (OR) during the same period The two groups were matched in terms of type of resection, tumor size, and severity of cirrhosisResults: One patient underwent conversion to an open approach Laparoscopic approach resulted in shorter operating time (150 mm, P 0 044) and towel blood loss (258 ml. P 0 008) There was no difference HI perloperative morbidity and mortality rate, laparoscopic approach was associated with a shorter hospital stay (6 3 days. P 0 039) After a mean follow up of 32 months, disease tree survival and overall survival were 40 2 and 23 3 months for laparoscopic group. and 47 7 and 31 4 months for OR group (1) NS)Conclusion: Laparoscopic resection of HCC is feasible and safe in selected patients and can result in good surgical results, with similar outcomes in terms of overall and disease-free survival. J Surg Oncol 2010, 102 82-86 (C) 2010 Wiley-Liss. Inc