2-azaadamantane N-oxyl (AZADO) and 1-Me-AZADO:: Highly efficient organocatalysts for oxidation of alcohols
2-azaadamantane N-oxyl (AZADO) and 1-Me-AZADO:: Highly efficient organocatalysts for oxidation of alcohols
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DOI：
10.1021/ja0620336
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发表时间：
2006-07-05
影响因子：
15
通讯作者：
Iwabuchi, Yoshiharu
中科院分区：
文献类型：
--
作者：
Shibuya, Masatoshi;Tomizawa, Masaki;Iwabuchi, Yoshiharu
报道了一种稳定的氮氧自由基类催化剂2-氮杂金刚烷-N-氧基(AZADO)和1-Me-AZADO的开发，用于醇的高效氧化。AZADO和1-Me-AZADO对TEMPO表现出优异的催化效率，以极高的产率将各种空间受阻的醇转化为相应的羰基化合物。
Development of a stable nitroxyl radical class of catalysts, 2-azaadamantaneN-oxyl (AZADO) and 1-Me-AZADO, for highly efficient oxidation of alcohols is described. AZADO and 1-Me-AZADO exhibit superior catalytic proficiency to TEMPO, converting various sterically hindered alcohols to the corresponding carbonyl compounds in excellent yields.