Airborne SARS-CoV-2 Is Rapidly Inactivated by Simulated Sunlight
Airborne SARS-CoV-2 Is Rapidly Inactivated by Simulated Sunlight
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DOI：
10.1093/infdis/jiaa334
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发表时间：
2020-08-15
影响因子：
6.4
通讯作者：
Dabisch, Paul
中科院分区：
文献类型：
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作者：
Schuit, Michael;Ratnesar-Shumate, Shanna;Dabisch, Paul
气溶胶代表了新冠肺炎的一条潜在传播途径。本研究考察了模拟日照、相对湿度和悬浮基质对SARS-CoV-2在气溶胶中稳定性的影响。模拟日照和基质对病毒的衰减率有显著影响。相对湿度本身并不影响衰减率；然而，观察到相对湿度和其他因素之间的微小交互作用。模拟唾液、冬末秋初模拟日照和夏季模拟日照的平均衰减率分别为0.121+/-0.017分钟(90%损失，19分钟)和0.306+/-0.097分钟(90%损失，8分钟)。在所有相对湿度水平上，在没有模拟阳光的情况下，平均衰减率为0.008+/-0.011分钟(-1)(90%损失，286分钟)。这些结果表明，SARS-CoV-2气溶胶传播的可能性可能取决于环境条件，特别是阳光。这些数据可能有助于制定缓解战略，最大限度地减少气溶胶传播的可能性。
Aerosols represent a potential transmission route of COVID-19. This study examined effect of simulated sunlight, relative humidity, and suspension matrix on stability of SARS-CoV-2 in aerosols. Simulated sunlight and matrix significantly affected decay rate of the virus. Relative humidity alone did not affect the decay rate; however, minor interactions between relative humidity and other factors were observed. Mean decay rates ( SD) in simulated saliva, under simulated sunlight levels representative of late winter/early fall and summer were 0.121 +/- 0.017 min(-1) (90% loss, 19 minutes) and 0.306 +/- 0.097 min(-1) (90% loss, 8 minutes), respectively. Mean decay rate without simulated sunlight across all relative humidity levels was 0.008 +/- 0.011 min(-1) (90% loss, 286 minutes). These results suggest that the potential for aerosol transmission of SARS-CoV-2 may be dependent on environmental conditions, particularly sunlight. These data may be useful to inform mitigation strategies to minimize the potential for aerosol transmission.