Non-Invasive Prenatal Testing for Down's Syndrome: Pregnant Women's Views and Likely Uptake
Non-Invasive Prenatal Testing for Down's Syndrome: Pregnant Women's Views and Likely Uptake
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DOI：
10.1159/000353523
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发表时间：
2013-01-01
影响因子：
1.7
通讯作者：
Chitty, L. S.
中科院分区：
文献类型：
--
作者：
Lewis, C.;Silcock, C.;Chitty, L. S.
背景：英国即将将唐氏综合症无创产前检测 (NIPT) 纳入国家资助的常规产前护理中。方法：我们对 40 名孕妇进行了定性的一对一访谈，以确定她们对使用 NIPT 治疗唐氏综合症的看法。结果：绝大多数女性认为 NIPT 是产前护理的积极进步，强调了高度准确且可以在怀孕早期进行的安全测试的许多实际和心理优势。人们担心检测可能会变得常规化，并且女性可能会感到没有理由拒绝由值得信赖的健康专业人士提供的血液检测，从而产生检测压力；还注意到对残疾人社区的影响以及拒绝检测的妇女的耻辱。尽管如此，绝大多数女性表示她们可能会使用 NIPT，其中包括目前拒绝筛查的一半女性。妇女更喜欢由助产士提供测试前和测试后咨询。结论：成功地将 NIPT 引入常规产前护理需要指导方针和咨询策略，以确保以保障妇女知情同意的方式为妇女提供这项测试。 (C) 2013 S. Karger AG，巴塞尔
Background: The introduction of non-invasive prenatal testing (NIPT) for Down's syndrome into routine state-funded antenatal care in the UK is approaching. Methods: We conducted qualitative one-to-one interviews with 40 pregnant women to ascertain their views on using NIPT for Down's syndrome. Results: The overwhelming majority of women viewed NIPT as a positive advancement in prenatal care, highlighting numerous practical and psychological advantages of a safe test that was highly accurate and could be conducted early in pregnancy. Concerns raised were that testing could become routinised, and that pressure to test might occur with women feeling less justified in declining a blood test that is available and offered by trusted health professionals; the impact on the disabled community and stigma for women who decline testing was also noted. Nevertheless, the vast majority of women said they would be likely to use NIPT, including half of the women who currently decline screening. Women's preference was for pre- and post-test counselling to be delivered by a midwife. Conclusion: The successful introduction of NIPT into routine prenatal care will require guidelines and counselling strategies which ensure women are offered this test in a way which safeguards informed consent. (C) 2013 S. Karger AG, Basel