Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target.

Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target.
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DOI:
10.1172/jci20364
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发表时间:
2003-11
期刊:
The Journal of clinical investigation
影响因子:
--
通讯作者:
Roger S Smith;B. Iglewski
Roger S Smith;B. Iglewski
中科院分区:
其他
文献类型:
--
作者:
Roger S Smith;B. Iglewski

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铜绿假单胞菌有两个完整的群体感应系统。这两个系统已被证明是重要的假单胞菌的毒力在多种模式的感染。因此,这些系统为新型抗微生物药物提供了独特的靶标。
Pseudomonas aeruginosa has two complete quorum-sensing systems. Both of these systems have been shown to be important for Pseudomonas virulence in multiple models of infection. Thus, these systems provide unique targets for novel antimicrobial drugs.