Experimental two-step universal adhesives bond durably in a challenging high C-factor cavity model.
Experimental two-step universal adhesives bond durably in a challenging high C-factor cavity model.
复制标题
实验性两步通用粘合剂可在具有挑战性的高 C 系数空腔模型中持久粘合。
DOI：
10.1016/j.dental.2022.11.021
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Van Meerbeek B.
中科院分区：
文献类型：
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作者：
Tang C;Ahmed MH;Yao C;Mercelis B;Yoshihara K;Peumans M;Van Meerbeek B.
ObjectivesTo determine bonding effectiveness of experimental 2-step universal adhesives（UAs）to high-C-factor class-I cavity-bottom dentin and to assess the potential bond-strength contribution of a additional fluidic composite layer.包括施加基于10-MDP的底漆，随后施加具有15-20- 100重量%的疏水粘合剂树脂，µm膜厚，仅填料不同，称为BZF-21（二氧化硅和玻璃填料），BZF-29（二氧化硅填料）和BZF-29_hv（较高的二氧化硅-填料负载导致较高的粘度），全部通过GC制备，沿着三种代表性的商业粘合剂，Clearfil SE Bond 2（C-SE2，Kuraray Noritake），G-Premium Bond（G-PrB、GC）和OptiBond FL（Opti-FL，Kerr），比较研究了它们的“即时”和“老化”（50，000次热循环）微拉伸粘结强度（μTBS），当以蚀刻和冲洗（E&R）或自蚀刻（SE）模式施加时，高C因子I类洞底牙本质（n = 10; 10个实验组）。另外四个实验组涉及额外应用可流动复合材料G-AsiaUniversal Flo（GC），其用作与粘合剂BZF-29和G-PrB组合的中间衬垫，并再次以E&R或SE模式应用。使用线性混合效应（LME）建模和线性回归分析进行统计分析（p < 0.05）。结果与金标准E&R Opti-FL和SE C-SE 2粘合剂相比，所有2步UA的表现相似，除了在E&R模式中应用的BZF-29_hv的老化μTBS，并且显著优于1步UA G-PrB。仅记录了在E&R模式下应用的2步UA在老化时μTBS的显著降低。额外的可流动复合层显着提高了G-PrB的μTBS. Significance实验2步UA在具有挑战性的高C因子I类腔模型中显示出良好的粘接性能，与多步黄金标准E&R和SE粘合剂相当，并且优于所研究的1步UA的上级。一个额外的应用可流动的复合层补偿的1-步骤UA在高C-因子腔模型的较低的粘接效率。
ObjectivesTo determine the bonding effectiveness of experimental 2-step universal adhesives (UAs) to high C-factor class-I cavity-bottom dentin and to assess the potential bond-strength contribution of an additional flowable composite layer.MethodsThree experimental 2-step UA formulations, involving the application of a 10-MDP-based primer followed by a hydrophobic adhesive resin with a 15-to-20-µm film thickness and differing only for filler, referred to as BZF-21 (silica and bioglass filler), BZF-29 (silica filler) and BZF-29_hv (higher silica-filler loading resulting in a higher viscosity), all prepared by GC, along with three representative commercial adhesives, Clearfil SE Bond 2 (C-SE2, Kuraray Noritake), G-Premio Bond (G-PrB, GC) and OptiBond FL (Opti-FL, Kerr), were comparatively investigated for their ‘immediate’ and ‘aged’ (50,000 thermocycles) micro-tensile bond strength (μTBS), when applied either in etch-and-rinse (E&R) or self-etch (SE) mode, to high C-factor class-I cavity-bottom dentin (n = 10; 10 experimental groups). Four additional experimental groups involved the extra application of the flowable composite G-ænial Universal Flo (GC), employed as an intermediate liner in combination with the adhesives BZF-29 and G-PrB and again applied both in E&R or SE mode. Statistical analysis was performed using linear mixed-effects (LME) modelling and linear regression analysis (p < 0.05).ResultsAll 2-step UAs performed similarly when compared to the gold-standard E&R Opti-FL and SE C-SE2 adhesives, except for the aged μTBS of BZF-29_hv applied in E&R mode, and significantly outperformed the 1-step UA G-PrB. Significant reduction in μTBS upon aging was only recorded for 2-step UAs applied in E&R mode. The extra flowable composite layer significantly improved G-PrB’s μTBS.SignificanceThe experimental 2-step UAs revealed favorable bonding performance in the challenging high C-factor class-I cavity model, comparable to that of the multi-step gold-standard E&R and SE adhesives and superior to that of the 1-step UA investigated. An additionally applied flowable composite layer compensated for the lower bonding effectiveness of the 1-step UA in the high C-factor cavity model.