Gender differences in geriatric syndromes as mental illness and nervous system diseases in hospitalized Thai older patients
Gender differences in geriatric syndromes as mental illness and nervous system diseases in hospitalized Thai older patients
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DOI：
10.1111/psyg.12679
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发表时间：
2021-04-13
期刊：
影响因子：
2
通讯作者：
Shieh, Fu-An
中科院分区：
文献类型：
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作者：
Suanrueang, Passakorn;Shen, Yong-Jiang;Shieh, Fu-An
背景老年人受精神和神经系统疾病的影响不同，性别在影响老年疾病的分化中起着重要作用。因此，本研究的特点是老年综合征住院老年泰国patients.Methods反映性别差异的疾病发生的可能性，从公共卫生部网站，泰国获得的历史数据进行计算。我们选取了2014年至2018年公立医院住院部收治的60岁及以上精神障碍和神经系统疾病老年患者，每年统计超过16万例。结果与老年女性相比，老年男性4种精神障碍的OR值和95%可信区间（CI）均高于老年女性：药物滥用（5.74，5.08-6.49）、酗酒（5.66，5.44-5.89）、行为问题（1.34，1.31-1.37）和精神分裂症（1.10，1.06-1.14）。老年男性的发病率较低，三种精神疾病的发病率相同：神经质问题（0.46，0.44-0.49），情绪障碍（0.58，0.56-0.60）和痴呆（0.91，0.88-0.94）。对于神经系统疾病，男性癫痫的发病率相似（1.67，1.63-1.72），脑瘫（1.61，1.57-1.65）、神经系统炎性疾病（1.53，1.46-1.60），缺血性发作（1.42，1.36-1.48），其他神经系统疾病（1.20; 1.18-1.22）和帕金森病（1.15，1.12-1.19）。相比之下，老年男性多发性硬化症的发病率较低，（0.55，0.35-0.86），偏头痛（0.66，0.62-0.70）和阿尔茨海默病（0.75，0.71-0.78）。结论准确描述老年综合征的性别差异可以更好地为适当的早期发现和预防政策提供信息，并促进发展对影响老年男女健康的各种问题的治疗和干预。
Background Older persons are affected by mental and neurological disorders differently, and gender plays a significant role influencing geriatric disorder differentiation. Accordingly this study characterized gender differences in geriatric syndromes among hospitalized elderly Thai patients.Methods Probabilities of disease occurrence reflecting gender differences were calculated using historical data obtained from the Ministry of Public Health website, Thailand. We selected older patients aged 60 years and above admitted to inpatient departments in public hospitals with mental disorders and nervous system diseases from 2014 to 2018, counting over 160 000 cases each year. Descriptive statistics and odds ratios (ORs) were used to analyse and demonstrate gender differences.Results Compared to older females, older males had higher occurrences of four mental disorders revealed by OR and 95% confidence interval (CI) values: substance abuse (5.74, 5.08-6.49), alcohol use (5.66, 5.44-5.89), behavioural problems (1.34, 1.31-1.37), and schizophrenia (1.10, 1.06-1.14). Lower incidences for older males were seen in the same values for three mental disorders: neurotic issues (0.46, 0.44-0.49), mood disorders (0.58, 0.56-0.60), and dementia (0.91, 0.88-0.94). For neurological disorders, men had similar higher incidences for epilepsy (1.67, 1.63-1.72), cerebral palsy (1.61, 1.57-1.65), nervous system inflammatory diseases (1.53, 1.46-1.60), ischaemic attacks (1.42, 1.36-1.48), miscellaneous other nervous disorders (1.20; 1.18-1.22), and Parkinson's disease (1.15, 1.12-1.19). By contrast, older men had lower incidences of multiple sclerosis (0.55, 0.35-0.86), migraines (0.66, 0.62-0.70), and Alzheimer's disease (0.75, 0.71-0.78).Conclusion Accurate characterization of gender differences in geriatric syndromes can better inform policies for appropriate early detection and prevention, and contribute to the development of treatment and intervention for various issues affecting elderly men and women's health.