Extradural cryptococcoma at the sacral spine without bone involvement in an immunocompetent patient.

Extradural cryptococcoma at the sacral spine without bone involvement in an immunocompetent patient.
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DOI:
10.1007/s00776-013-0413-2
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发表时间:
2014-11
影响因子:
1.7
通讯作者:
Sudo, Akihiro
Sudo, Akihiro
中科院分区:
医学4区
文献类型:
--
作者:
Asanuma, Yumiko;Fujimoto, Hajime;Nakabayashi, Hiroshi;Akeda, Koji;Asanuma, Kunihiro;Tanaka, Masaru;Nagakura, Takeshi;Miura, Yoshihiro;Iino, Takahiro;Ogawa, Kunikazu;Kasai, Yuichi;Sudo, Akihiro

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新型隐球菌是一种被包裹的酵母样真菌,存在于鸟类排泄物、土壤和腐烂木材中[1]。呼吸道是酵母吸入引起隐球菌感染的主要途径,感染可传播至大多数其他器官[2,3],尽管主要靶器官是肺和中枢神经系统(CNS)[4]。CNS受累病例中最常见的表现是脑膜炎和脑膜脑炎[5,6]。CNS隐球菌感染的硬膜外病变是一种罕见的实体,通常伴有骨髓炎[7-14]。隐球菌感染主要见于免疫功能低下的患者[2,4,5]。然而,高达10-40%的报告病例发生在免疫功能正常的个体中[5,6,15,16]。
Cryptococcus neoformans is an encapsulated yeast-like fungus found in avian excreta, soil, and decayed wood [1]. The respiratory tract is the primary route of cryptococcal infection from yeast inhalation, and the infection can disseminate to most other organs [2, 3], although the main target organs are the lungs and the central nervous system (CNS)[4]. The most common manifestations in cases of CNS involvement are meningitis and meningoencephalitis [5, 6]. An extradural lesion of cryptococcal infection in the CNS is a rare entity that is usually accompanied by osteomyelitis [7–14]. Cryptococcal infection is mostly found in immunocompromised patients [2, 4, 5]. However, up to 10–40% of reported cases have been in immunocompetent individuals [5, 6, 15, 16].
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发表时间: 2001-09-01
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