Time resolved properties of acoustic pulses generated in water and in soft tissue by pulsed proton beam irradiation--a possibility of doses distribution monitoring in proton radiation therapy.
Time resolved properties of acoustic pulses generated in water and in soft tissue by pulsed proton beam irradiation--a possibility of doses distribution monitoring in proton radiation therapy.
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脉冲质子束照射在水和软组织中产生的声脉冲的时间分辨特性——质子放射治疗中剂量分布监测的可能性。
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
T. Inada
中科院分区：
文献类型：
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作者：
J. Tada;Y. Hayakawa;K. Hosono;T. Inada
观测到了脉冲质子束在水和软组织中产生的时间分辨声脉冲。通过TOF测量，临床应用的束流强度的深度剂量分布的空间分辨率估计为3 mm。考察了声信号强度对介质温度的依赖关系。声脉冲强度与每脉冲吸收剂量的比例也得到了证实。这些结果表明，临床应用于监测脉冲质子束照射期间患者体内的剂量分布是可能的。
Time-resolved acoustic pulses generated in water and in soft tissue by pulsed proton beam irradiation were observed. The spatial resolution of depth dose distribution in the clinically applied beam intensity is estimated about 3 mm by means of TOF measurement. The dependence of the acoustic signal intensity on the temperature of medium was examined. Proportionality of acoustic pulse intensity to absorbed dose per pulse was confirmed as well. These results suggest the possibility of clinical application to monitor dose distribution in the patient's body during irradiation of pulsed proton beam.