The role of early-life socioeconomic status in breast cancer incidence and mortality: unraveling life course mechanisms.
The role of early-life socioeconomic status in breast cancer incidence and mortality: unraveling life course mechanisms.
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DOI：
10.1177/0898264311422744
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发表时间：
2012-03
影响因子：
2.8
通讯作者：
Anikputa B
中科院分区：
文献类型：
--
作者：
Pudrovska T;Anikputa B
我们研究了(1)早期社会经济地位（SES）的各个维度如何影响乳腺癌的发病和生存，以及(2)女性成年后的特征在多大程度上介导了早期生活条件与乳腺癌之间的关联。我们对威斯康星纵向研究中4275名妇女的数据应用了Cox回归模型和分解分析。母亲的教育水平和早期家庭收入水平越高，患乳腺癌的风险越大。母亲受教育程度的影响受女性成年后社会经济地位和生育行为的中介。父亲受教育程度与乳腺癌死亡率呈负相关，但这种影响完全由女性自身受教育程度介导。这项研究确定了早期社会环境与乳腺癌发病和死亡率之间的联系机制。研究结果强调了社会因素在乳腺癌发病率和生存率中的作用。
We examine (1) how breast cancer onset and survival are affected by various dimensions of early-life socioeconomic status (SES), and (2) the extent to which women's characteristics in adulthood mediate the associations between early-life conditions and breast cancer. We apply Cox regression models and a decomposition analysis to the data from the 4,275 women in the Wisconsin Longitudinal Study. Higher levels of mothers’ education and early-life family income were associated with a greater risk of breast cancer incidence. The effect of mothers’ education was mediated by women's adult SES and reproductive behaviors. Fathers’ education was related negatively to breast cancer mortality, yet this effect was fully mediated by women's own education. This study identifies mechanisms linking early-life social environment to breast cancer onset and mortality. The findings emphasize the role of social factors in breast cancer incidence and survival.
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影响因子：
5.4
作者：
Lynch, JW;Kaplan, GA;Salonen, JT
通讯作者：
Salonen, JT
DOI：
10.1073/pnas.0502433102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Erikson, R;Goldthorpe, JH;Cox, DR
通讯作者：
Cox, DR
影响因子：
3.5
作者：
KAHN, JR;ANDERSON, KE
通讯作者：
ANDERSON, KE
影响因子：
9.1
作者：
AXINN, WG;THORNTON, A
通讯作者：
THORNTON, A
影响因子：
2.7
作者：
Carr, D
通讯作者：
Carr, D