PIP-DB: the Protein Isoelectric Point database

PIP-DB: the Protein Isoelectric Point database
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DOI:
10.1093/bioinformatics/btu637
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发表时间:
2015-01-15
期刊:
影响因子:
5.8
通讯作者:
Flower, Darren R.
Flower, Darren R.
中科院分区:
生物学3区
文献类型:
--
作者:
Bunkute, Egle;Cummins, Christopher;Flower, Darren R.

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蛋白质的等电点或 pI 对应于其净表面电荷为零时的溶液 pH 值。从溶液生物化学的早期开始,pI 就已经被记录和报道,因此有关 pI 的文献报道比比皆是。蛋白质等电点数据库 (PIP-DB) 收集并整理了这些数据,以提供一个日益全面的数据库,用于比较和基准测试。我们开发了一个 Web 应用程序来存储该数据库并提供对这一独特资源的公共访问。 PIP-DB 是一个支持 Web 的 SQL 数据库,具有 HTML GUI 前端。 PIP-DB 可以在一系列属性中进行完全搜索。
A protein's isoelectric point or pI corresponds to the solution pH at which its net surface charge is zero. Since the early days of solution biochemistry, the pI has been recorded and reported, and thus literature reports of pI abound. The Protein Isoelectric Point database (PIP-DB) has collected and collated these data to provide an increasingly comprehensive database for comparison and benchmarking purposes. A web application has been developed to warehouse this database and provide public access to this unique resource. PIP-DB is a web-enabled SQL database with an HTML GUI front-end. PIP-DB is fully searchable across a range of properties.