Over one-half billion years of head conservation?: Expression of an ems class gene in Hydractinia symbiolongicarpus (Cnidaria: Hydrozoa)
Over one-half billion years of head conservation?: Expression of an ems class gene in Hydractinia symbiolongicarpus (Cnidaria: Hydrozoa)
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DOI：
10.1073/pnas.95.7.3673
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发表时间：
1998-03-31
影响因子：
11.1
通讯作者：
Buss, LW
中科院分区：
文献类型：
--
作者：
Mokady, O;Dick, MH;Buss, LW
我们报道了从水生动物Hydractinia symbiolongarpus中分离到的空气门类同源结构域基因Cn-ems，这是第一个在低等后生动物中发现的空气门类同源结构域基因，Cn-ems在胃体动物的头部，特别是在下体带的内胚层上皮细胞中表达，Cn-ems在缺乏带的生殖体中不表达，实验转换的后部区域的浮游幼虫头部结构上调基因的表达，这些研究结果表明，协会的ems类基因与头部结构之前的双边对称性的演变。
We report the isolation of an empty spiracles class homeodomain-containing gene, Cn-ems, from the hydrozoan Hydractinia symbiolongicarpus, the first gene of this class characterized in a lower metazoan, Cn-ems was found to be expressed in the head of gastrozooids, specifically in endodermal epithelial cells of the taeniolae of the hypostome, Cn-ems is not expressed in gonozooids, which lack taeniolae, Experimental conversion of the posterior region of the planula larva into head structures up-regulates expression of the gene, These findings establish that the association of ems-class genes with head structures preceded the evolution of bilateral symmetry.