Eccentricity dependent changes of density, spacing and packing arrangement of parafoveal cones
Eccentricity dependent changes of density, spacing and packing arrangement of parafoveal cones
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DOI：
10.1111/opo.12053
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发表时间：
2013-07-01
影响因子：
2.9
通讯作者：
Lombardo, Giuseppe
中科院分区：
文献类型：
--
作者：
Lombardo, Marco;Serrao, Sebastiano;Lombardo, Giuseppe
目的研究视锥细胞密度和间距的分布以及视锥细胞镶嵌的排列方式与视网膜偏心率的关系。方法采用自适应光学视网膜照相机（rtx 1，www.imagine-eyes.com）对19名健康志愿者的视锥镶嵌区进行成像。使用80 × 80像素的采样窗口，在距中央凹沿着双眼鼻侧和颞侧视网膜的250-、450-、650-和1100-m偏心距下，估计每例受试者（双眼）的视锥密度和间距。通过变异系数（CoV）计算锥体密度和间距的受试者间和受试者内变异。使用Voronoi分析评估锥体堆积排列;计算在200- 1050-m偏心度的水平子午线上锥体镶嵌的1024 x128像素图像切片上进行。结果视锥密度的个体间变异在10%~ 15%之间（p
Purpose To investigate the distribution of cone density and spacing as well as the preferred packing arrangement of the cone mosaic as a function of retinal eccentricity. Methods An adaptive optics retinal camera (rtx1, www.imagine-eyes.com) was used to obtain images of the parafoveal cone mosaic in nineteen healthy volunteers. Cone density and spacing were estimated for each subject (both eyes) using a sampling window of 80x80 pixels, at 250-, 450-, 650- and 1100-m eccentricities from the fovea along the nasal and temporal retina of both eyes. The inter-subject and intra-subject variation of cone density and spacing were calculated via Coefficient of Variation (CoV). Cone packing arrangement was assessed using Voronoi analysis; calculations were done over 1024x128 pixels image sections of the cone mosaic across the horizontal meridian from 200- to 1050-m eccentricities. Results The inter-subject variation of parafoveal cone density ranged between 10% and 15% (p