[Study on the antioxidative effect of Safflor Yellow].
[Study on the antioxidative effect of Safflor Yellow].
复制标题
DOI：
--
复制
发表时间：
2004-05
期刊：
影响因子：
--
通讯作者：
Ming Jin;Jinrong Li;Wei Wu
中科院分区：
文献类型：
--
作者：
Ming Jin;Jinrong Li;Wei Wu
目的观察红花黄（SY）的抗氧化作用。方法采用1,10-菲罗啉- fe2 +氧化法检测SY对羟基自由基的清除作用。采用硫代巴比妥酸比色法测定小鼠肝悬液的脂质过氧化。用比色法测定血细胞计数。结果对羟基自由基的清除作用具有1.39 ~ 3.42 g × L(-1) SY的剂量依赖性。77.8 ~ 776.1 mg × L(-1) SY对小鼠肝悬液过氧化抑制作用呈剂量依赖性。血细胞导尿剂量依赖性减弱37.1 ~ 297.1 mg × L(-1) SY。结论红花中SY具有抗氧化作用。
OBJECTIVE To observe the antioxidative effect of Safflor Yellow (SY). METHOD Hydroxyl radical scavenge effect of SY was tested with 1,10-phenanthroline-Fe2+ oxidative assay. Lipid peroxidation of mouse liver suspension was measured with thiobarbituric acid colorimetry technique. Hemocytocatheresis was determined with colorimetry. RESULT Hydroxyl radical could be scavenged by 1.39 to 3.42 g x L(-1) SY dose dependently. Mouse liver suspension peroxidation was inhibited by 77.8 to 776.1 mg x L(-1) SY dosage dependently. Hemocytocatheresis was attenuated by 37.1 to 297.1 mg x L(-1) SY dose dependently. CONCLUSION SY is an antioxidative part of Carthamus tinctorius.