TOPOGRAPHICAL DISTRIBUTION OF ARSENIC MANGANESE AND SELENIUM IN THE NORMAL HUMAN BRAIN
TOPOGRAPHICAL DISTRIBUTION OF ARSENIC MANGANESE AND SELENIUM IN THE NORMAL HUMAN BRAIN
复制标题
DOI：
10.1016/0022-510x(79)90173-4
复制
发表时间：
1979-01-01
影响因子：
4.4
通讯作者：
HEYDORN K
中科院分区：
文献类型：
--
作者：
LARSEN N A;PAKKENBERG H;HEYDORN K
本文测定了5名15~81岁正常人24个脑区湿组织重中As、Mn、Se的含量。用中子活化分析放化分离法测定各样品中3种元素的浓度。这三种元素都显示出不同的分布模式。个体之间的差异在一些但不是所有的大脑区域被发现，导致个体之间的变异系数约为30%的砷，10%的锰和20%的硒。砷可能与脑组织的脂肪相有关，锰与干物质有关，硒与脑组织的水相有关。
The concentrations of As, Mn and Se per gram wet tissue weight were determined in samples from 24 areas of normal human brains from 5 persons with ages ranging from 15-81 yr of age. The concentrations of the 3 elements were determined for each sample by neutron activation analysis with radiochemical separation. Distinct patterns of distribution were shown for each of the 3 elements. Variations between individuals were found for some but not all brain areas, resulting in coefficients of variation between individuals of about 30% for As, 10% for Mn and 20% for Se. Arsenic is probably associated with the lipid phase, Mn with the dry matter and Se with the aqueous phase of brain tissue.