C5a complement and cytokine signaling mediate the pronociceptive effects of complex regional pain syndrome patient IgM in fracture mice.
C5a complement and cytokine signaling mediate the pronociceptive effects of complex regional pain syndrome patient IgM in fracture mice.
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DOI：
10.1097/j.pain.0000000000002150
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发表时间：
2021-05-01
期刊：
影响因子：
7.4
通讯作者：
Kingery WS
中科院分区：
文献类型：
--
作者：
Shi X;Guo TZ;Li WW;Birklein F;Escolano FL;Herrnberger M;Clark JD;Kingery WS
CRPS 患者 IgM 介导的 C5a 补体信号传导在骨折小鼠中具有促伤害性。 C5a 补体和细胞因子信号传导介导 CRPS 患者 IgM 对骨折小鼠皮肤和脊髓的伤害感受作用。
CRPS patient IgM-mediated C5a complement signaling is pronociceptive in fracture mice. C5a complement and cytokine signaling mediates CRPS patient IgM pronociceptive effects in the skin and spinal cord of fracture mice.