Two to Ten Years: Developmental Trajectories of Joint Attention in Children With ASD Who Received Targeted Social Communication Interventions
Two to Ten Years: Developmental Trajectories of Joint Attention in Children With ASD Who Received Targeted Social Communication Interventions
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DOI：
10.1002/aur.1360
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发表时间：
2014-04-01
期刊：
影响因子：
4.7
通讯作者：
Kasari, Connie
中科院分区：
文献类型：
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作者：
Gulsrud, Amanda C.;Hellemann, Gerhard S.;Kasari, Connie
这项研究跟踪了40名儿童，他们参加了一项随机对照早期干预试验（Kasari等人）。从幼儿期（2-5岁）到小学年龄（8-10岁）。为了充分利用现有的纵向数据，一般线性混合模型是主要的分析方法。在测量期间的五个时间点的基础上，估计这些儿童的联合注意力技能（指向，协调联合寻找，并显示）和表达性语言的结果的增长轨迹。这些儿童按照最后一次随访时的诊断（自闭症、自闭症谱系障碍（ASD）、未诊断）和他们最初的治疗组分配（联合注意、象征性游戏、控制）进行分组，并评估这些组之间的差异。结果表明，随着时间的推移，协调联合看和显示的联合注意力技能增加，并指出，在第一年增加了共同的兴趣，此后下降。这些轨迹受初始治疗分配和随访时诊断状态的影响。此外，交叉滞后面板分析揭示了早期指向和后来的语言发展之间的因果关系。这项研究强调了自闭症早期核心缺陷措施的纵向和发展重要性，并表明治疗和ASD治疗学可能会随着时间的推移影响这些技能的增长。Autism Res 2014，7：207-215. (c)2014年国际自闭症研究学会，Wiley Periodicals，Inc。
This study follows 40 children who were participants in a randomized controlled early intervention trial (Kasari et al.) from early childhood (2-5 years of age) to elementary school age (8-10 years). To fully utilize the available longitudinal data, the general linear mixed model was the primary analytical approach. The growth trajectories of joint attention skills (pointing, coordinated joint looking, and showing) and expressive language outcomes in these children were estimated based on five time points during the measurement period. The children were grouped by diagnosis at the last follow-up (autism, autism spectrum disorder (ASD), no diagnosis) and by their original treatment group assignment (joint attention, symbolic play, control), and differences between these groups were evaluated. Results showed that joint attention skills of coordinated joint looking and showing increased over time, and pointing to share interest increased over the first year measured and decreased thereafter. These trajectories were influenced by both original treatment assignment and diagnostic status at follow-up. In addition, a cross-lagged panel analysis revealed a causal relationship between early pointing and later language development. This study highlights the longitudinal and developmental importance of measures of early core deficits in autism, and suggests that both treatment and ASD symptomatology may influence growth in these skills over time. Autism Res 2014, 7: 207-215. (c) 2014 International Society for Autism Research, Wiley Periodicals, Inc.