Quantifying Uncertainty in Estimations of the Total Weight of Drugs in Groups of Complex Matrices: Using the Welch–Satterthwaite Equation
Quantifying Uncertainty in Estimations of the Total Weight of Drugs in Groups of Complex Matrices: Using the Welch–Satterthwaite Equation
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DOI：
10.1111/1556-4029.13351
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发表时间：
2017-07
影响因子：
1.6
通讯作者：
I. Alberink;Annette Sprong;A. Bolck;P. Vergeer
中科院分区：
文献类型：
--
作者：
I. Alberink;Annette Sprong;A. Bolck;P. Vergeer
本文介绍了一种定量估计查获物品组中毒品总量的方法，包括精确度的量化。以前关于这个主题的工作是基于正态分布的测量和分组的项目与一个共同的相对标准偏差的假设。在实践中，这些假设经常被违反，例如，对于点质量为0的数据，或者如果组中的某些项目具有非常高的标准差。本文描述的方法是基于韦尔奇和Satterthwaite的工作，并没有假设恒定的相对标准偏差。案例的例子描述的方法被应用，并进行了模拟研究，这两种方法都适用。在这种情况下，这两种方法都表现得相当好。如果共同相对标准偏差的假设显然不适用，建议使用所述方法。
In this paper, a method is described to quantify estimations of the total amount of drugs in groups of seized items, including quantification of the precision. Previous work on this topic was based on the assumptions of normally distributed measurements and grouping of items with a common relative standard deviation. In practice, these assumptions are often violated, for example, for data with point masses at 0, or if certain items in a group have a very high standard deviation. The method described in this paper is based on work by Welch and Satterthwaite and does not assume constant relative standard deviations. Case examples are described for which the method is applied, and simulation studies are carried out for which both methods are applied. In the cases, both methods perform reasonably well. If the assumption of common relative standard deviations clearly does not apply, it is advised to use the method described.