Temperature-controlled release of catechol dye in thermosensitive phenylboronate-containing copolymers: A quantitative study
Temperature-controlled release of catechol dye in thermosensitive phenylboronate-containing copolymers: A quantitative study
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DOI：
10.1016/j.eurpolymj.2010.03.020
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发表时间：
2010-06
影响因子：
6
通讯作者：
Gaëlle Carré de Lusançay;S. Norvez;I. Iliopoulos
中科院分区：
文献类型：
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作者：
Gaëlle Carré de Lusançay;S. Norvez;I. Iliopoulos
用紫外-可见光谱法研究了两种含苯硼酸共聚物与邻苯二酚染料茜素红S（ARS）的可逆络合反应。基于N-异丙基丙烯酰胺（NIPAM）的第一种共聚物是热敏的，而基于N，N-二甲基丙烯酰胺（DMAM）的第二种共聚物不是热敏的。研究结果在两个不同的温度下，在pH7.4的磷酸盐缓冲液中的主客体结合常数的定量测定。在热敏性共聚物的相变温度Tp以上，结合常数降低6倍，比在非热敏性共聚物的情况下降低两倍。这种行为与基于NIPAM的共聚物的线圈到小球的转变有关，其在Tp以上排出染料标记物。
The reversible complex formation between two phenylboronic acid bearing copolymers and the catechol dye Alizarin Red S (ARS) was studied by dialysis experiments coupled with UV–visible spectroscopy. The first copolymer based on N-isopropylacrylamide (NIPAM) is thermosensitive, whereas the second one based on N,N-dimethylacrylamide (DMAM) is not. The investigation resulted in the quantitative determination of the host–guest binding constants at two different temperatures at pH7.4 in phosphate buffer. Above the phase transition temperature Tp of the thermosensitive copolymer, the binding constant decreases by a factor of 6, twice more than in the case of the non-thermosensitive copolymer. This behaviour is related to the coil-to-globule transition of NIPAM-based copolymer, which above Tp expels the dye marker.