Experience in IVIg Therapy for Selected Women with Recurrent Reproductive Failure and NK Cell Expansion

Experience in IVIg Therapy for Selected Women with Recurrent Reproductive Failure and NK Cell Expansion
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对患有复发性生殖衰竭和 NK 细胞扩增的特定女性进行 IVIg 治疗的经验

DOI:
10.1111/aji.12217
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发表时间:
2014
影响因子:
3.6
通讯作者:
S. Sánchez‐Ramón
S. Sánchez‐Ramón
中科院分区:
医学3区
文献类型:
--
作者:
R. Ramos;Á. García‐Segovia;J. Gil;J. Carbone;Angel Aguarón de la Cruz;A. Seyfferth;B. Alonso;J. Alonso;J. A. Léon;D. Alecsandru;Elena Meliá;E. Carrillo de albornoz;D. Ordoñez;I. Santillán;V. Verdú;J. M. García Ruiz de Morales;M. López;Arturo López Larios;A. Sampalo;P. Caballero;L. Ortiz Quintana;E. Fernandez;S. Sánchez‐Ramón

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复发性生殖衰竭(RRF)与循环NK细胞的扩增有关,NK细胞是母体耐受、蜕膜血管发生和胚胎生长的关键细胞。本研究报告了我们对大量循环NK和/或NKT样细胞扩增的RRF女性患者(血液NKT细胞是T细胞的异质亚群,具有T细胞和NK细胞的特性)进行静脉注射免疫球蛋白(IVIg)治疗的经验。
Recurrent reproductive failure (RRF) has been associated with expansion of circulating NK cells, key cells for maternal tolerance, decidual vasculogenesis and embryo growth. This study reports our experience in intravenous immunoglobulin (IVIg) therapy of a large cohort of women with RRF with expanded circulating NK and/or NKT‐like cells (blood NKT cells are a heterogeneous subset of T cells that share properties of both T cells and NK cells).
DOI: 10.1093/humrep/deq179
发表时间: 2010-09-01
期刊: HUMAN REPRODUCTION
影响因子: 6.1
作者:
Stephenson, Mary D.;Kutteh, William H.;Liao, Chuanhong
通讯作者: Liao, Chuanhong