Neuronal loss in lumbar dorsal root ganglia after proximal compared to distal sciatic nerve resection: a quantitative study in the rat
Neuronal loss in lumbar dorsal root ganglia after proximal compared to distal sciatic nerve resection: a quantitative study in the rat
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DOI：
10.1016/0006-8993(89)91497-2
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发表时间：
1989-01
期刊：
影响因子：
2.9
通讯作者：
J. Ygge
中科院分区：
文献类型：
--
作者：
J. Ygge
在成年大鼠上研究了单侧坐骨神经近端（大腿）或远端（小腿近端）切断对L4-L 6背根神经节（DRG）神经元数量的影响。近端神经切除导致DRG神经元平均损失27%，而远端病变的平均细胞损失为7%，近端和远端坐骨神经切除之间的细胞损失差异非常显著（P<0.001）。
The effects of unilateral sciatic nerve resections at proximal (thigh) or distal (proximal calf) locations on L4–L6dorsal root ganglion (DRG) neuronal numbers have been studied in adult rats. Proximal nerve resection gave rise to a mean DRG neuronal loss of 27%, whereas in distal lesions a mean cell loss of 7% was found. This difference in cell loss between proximal and distal sciatic nerve resections is highly significant (P<0.001).