Subcutaneous fat in normal and diseased states - 1. Introduction
Subcutaneous fat in normal and diseased states - 1. Introduction
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DOI：
10.1016/j.jaad.2005.05.014
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发表时间：
2005-10-01
影响因子：
13.8
通讯作者：
James, WD
中科院分区：
文献类型：
--
作者：
Avram, MM;Avram, AS;James, WD
近年来，我们对脂肪组织生理学和功能的理解经历了巨大的转变。脂肪组织曾经被认为是一个被动的储存容器，具有固定数量的细胞和有限的用途，现在被认为是一个复杂的器官，具有重要的内分泌和代谢功能。现在已知，脂肪组织质量的增加和减少，如肥胖、厌食和脂肪代谢障碍中所见，对多个身体系统，包括免疫、生殖和造血系统具有深远的影响。因此，对脂肪组织的研究不仅对治疗肥胖、脂肪萎缩及其相关代谢和内分泌紊乱的人很重要，而且对那些专门从事人体最大脂肪组织细分（皮下脂肪）内疾病的内科和外科治疗的皮肤科医生也很重要。这篇介绍性文章是关于脂肪组织在正常和患病状态的系列文章的第一篇。
In recent years, our understanding of adipose tissue physiology and function has undergone an enormous transformation. Once considered a passive storage receptacle with a fixed number of cells and limited purpose, adipose tissue is now recognized as a complicated organ with important endocrine and metabolic functions. It is now known that both increased and decreased adipose tissue mass, as seen in obesity, anorexia, and lipodystrophy, have profound effects on multiple body systems, including immune, reproductive, and hematopoietic. The study of adipose tissue, therefore, is important not only for those who treat obesity, lipoatrophy, and their associated metabolic and endocrine derangements, but also for those dermatologists who specialize in the medical and surgical treatment of disorders within the body's largest adipose tissue subdivision, the subcutaneous fat. This introductory article is the first in a series about adipose tissue in normal and diseased states.