Electroanalysis of Hydrogen Peroxide at Boron Doped Diamond Electrode Modified by Silver Nanoparticles and Haemoglobin
Electroanalysis of Hydrogen Peroxide at Boron Doped Diamond Electrode Modified by Silver Nanoparticles and Haemoglobin
复制标题
DOI：
10.1016/j.electacta.2015.07.013
复制
发表时间：
2015-09-10
影响因子：
6.6
通讯作者：
Foord, John S.
中科院分区：
文献类型：
--
作者：
Jiang, Luyun;Hu, Jingping;Foord, John S.
报道了纳米银和血红蛋白修饰的硼掺杂金刚石电极对过氧化氢的电化学检测。在十六烷基溴化十六烷基三甲基溴化铵(CTAB)存在下电沉积得到的纳米银具有最佳的检测限、灵敏度和重现性。银纳米颗粒的存在有助于将血红蛋白以活性形式结合到电极上，从而显著提高电极对过氧化氢的响应。在两种改进剂的协同作用下，检测下限可达到1微米以下，并且在8 mm范围内具有良好的线性信号响应。在典型的生理水平上，葡萄糖、尿酸、抗坏血酸和多巴胺的干扰可以忽略不计。(C)爱思唯尔有限公司出版的2015年。
The electrochemical detection of H2O2 using boron doped diamond electrode modified by silver nanoparticles and haemoglobin is reported. Silver nanoparticle obtained from electrodeposition in the presence of cetyl hexadecylthmoniom bromide (CTAB) surfactant shows the best combination of detection limit, sensitivity and reproducibility. The presence of Ag nanoparticles helps bind haemoglobin to the electrode in an active form, leading to a significantly further increase of electrode response to H2O2. Detection limits below 1 mu M are achieved by a synergistic effect of both modifiers, and a good linear signal response is seen up to 8 mM. Interferences from glucose, uric acid, ascorbic acid and dopamine at typical physiological levels are shown to be negligible. (C) 2015 Published by Elsevier Ltd.